Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 3/20 | 0.55 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.55 |
| ▸ | NAMPT | P43490 | 5/20 | 0.52 |
| ▸ | TMPRSS2 | O15393 | 4/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.46 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.46 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.46 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3603275 | 0.92 | NAMPT (0.49) | SCDSCD5NAMPTTMPRSS2ESR2 | |
| SCHEMBL3606619 | 0.90 | TMPRSS2 (0.49) | SCDSCD5NAMPTTMPRSS2ESR2 | |
| SCHEMBL3602454 | 0.90 | RAF1 (0.47) | SCDSCD5NAMPTESR2NR1H2 | |
| SCHEMBL3596141 | 0.87 | TMPRSS2 (0.47) | SCDSCD5NAMPTTMPRSS2ESR2 | |
| SCHEMBL3605404 | 0.84 | NAMPT (0.63) | SCDSCD5NAMPTESR2ALDH1A1 | |
| SCHEMBL3599020 | 0.83 | SMN1; SMN2 (0.57) | SCDSCD5NAMPTTMPRSS2ESR2 | |
| SCHEMBL3603596 | 0.83 | SCD (0.53) | SCDSCD5NAMPTTMPRSS2ESR2 | |
| SCHEMBL3615748 | 0.83 | SCD (0.53) | SCDSCD5NAMPTESR2ALDH1A1 | |
| SCHEMBL3598199 | 0.83 | NAMPT (0.56) | SCDSCD5NAMPTESR2ALDH1A1 | |
| SCHEMBL3605783 | 0.82 | NAMPT (0.56) | SCDSCD5NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041696-A1 | Compounds | SMITHKLINE BEECHAM CORPORATION | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041696-A1 | Compounds | CYP11B2, SCD, CYP3A5 | SCD 2/4885SCD5 4/4885NAMPT 869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.