Methacrylic Acid

Methacrylic Acid

SCHEMBL3609865

C=C(C)C(=O)O.C=CC#N.C=CC=C.NC(=O)C=CC=Cc1ccccc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.43
HDAC3 O15379 2/20 0.41
HDAC4 P56524 2/20 0.41
HDAC1 Q13547 2/20 0.41
HDAC7 Q8WUI4 2/20 0.41
HDAC2 Q92769 2/20 0.41
HDAC10 Q969S8 2/20 0.41
HDAC11 Q96DB2 2/20 0.41
HDAC8 Q9BY41 2/20 0.41
HDAC6 Q9UBN7 2/20 0.41
HDAC9 Q9UKV0 2/20 0.41
HDAC5 Q9UQL6 2/20 0.41
MAOB P27338 5/20 0.39
CYP3A4 P08684 1/20 0.39
GLA P06280 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MAPT P10636 4/20 0.37
LMNA P02545 4/20 0.37
HTT P42858 2/20 0.37
ALDH1A1 P00352 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylonitrile SCHEMBL10577801 0.92 MCL1 (0.49) MCL1HDAC3HDAC4HDAC1HDAC7
Acrylonitrile SCHEMBL5153154 0.89 MCL1 (0.51) MCL1HDAC3HDAC4HDAC1HDAC7
Methacrylic Acid SCHEMBL10791017 0.88 HDAC3 (0.51) MCL1HDAC3HDAC4HDAC1HDAC7
Butadiene SCHEMBL6735917 0.84 HDAC3 (0.56) MCL1HDAC3HDAC4HDAC1HDAC7
Methacrylic Acid SCHEMBL863641 0.83 CYP3A4 (0.43) MCL1HDAC3HDAC4HDAC1HDAC7
Styrene SCHEMBL10702189 0.82 CYP3A4 (0.42) MCL1HDAC3HDAC4HDAC1HDAC7
Juarezic Acid SCHEMBL2246623 0.81 HDAC3 (0.50) MCL1HDAC3HDAC4HDAC1HDAC7
Styrene SCHEMBL465498 0.80 ALDH1A1 (0.45) MCL1CYP3A4GLATDP1MAPT
Styrene SCHEMBL28022328 0.80 ALDH1A1 (0.45) MCL1CYP3A4GLATDP1MAPT
Methacrylic Acid SCHEMBL437865 0.78 CYP3A4 (0.46) MCL1HDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7750066-B2 Treatment of aqueous compositions containing contaminants ERIN CONSULTING LIMITED (CA) 2010-07-06 US disclosed
US-20070244225-A9 Treatment of aqueous compositions containing contaminants ERIN CONSULTING LIMITED (CA) 2007-10-18 US disclosed
US-20060148933-A1 Treatment of aqueous compositions containing contaminants SUTHERLAND GEORGE 2006-07-06 US disclosed