SCHEMBL3610591

SCHEMBL3610591

COc1ccc(OC(=O)c2ccc(/C=C/C(=O)OCc3ccc(N)cc3N)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.47
LMNA P02545 4/20 0.47
MAPK1 P28482 1/20 0.47
KMT2A Q03164 5/20 0.47
MEN1 O00255 3/20 0.47
KDM4E B2RXH2 2/20 0.47
TDP1 Q9NUW8 2/20 0.45
ALDH1A1 P00352 2/20 0.45
GFER P55789 1/20 0.45
NPC1 O15118 1/20 0.45
F3 P13726 2/20 0.43
P4HB P07237 1/20 0.43
CALM1 P0DP23 1/20 0.43
RAB9A P51151 1/20 0.43
XDH P47989 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
APP P05067 1/20 0.42
GSK3B P49841 1/20 0.41
BCHE P06276 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL679197 0.92 MAPT (0.44) MAPTLMNAMAPK1KMT2AMEN1
SCHEMBL679772 0.92 MAPT (0.44) MAPTLMNAMAPK1KMT2AMEN1
SCHEMBL15316353 0.92 CA12 (0.44) MAPTKMT2AMEN1KDM4EALDH1A1
SCHEMBL27726790 0.92 KMT2A (0.52) MAPTLMNAKMT2AMEN1KDM4E
SCHEMBL13495603 0.90 AKR1B10 (0.44) MAPTLMNAKMT2AMEN1KDM4E
SCHEMBL28650120 0.88 MAPT (0.40) MAPTLMNAMAPK1KMT2AKDM4E
SCHEMBL1564456 0.88 MAPT (0.40) MAPTLMNAMAPK1KMT2AKDM4E
SCHEMBL15315054 0.87 ABCG2 (0.47) MAPTLMNAKMT2AALDH1A1NPC1
SCHEMBL28667421 0.86 MAPT (0.39) MAPTLMNAMAPK1KMT2AKDM4E
SCHEMBL1563402 0.86 MAPT (0.39) MAPTLMNAMAPK1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120092603-A1 LIQUID CRYSTAL DISPLAY DEVICE AND MANUFACTURING METHOD THEREFOR SHARP KABUSHIKI KAISHA (JP) 2012-04-19 US disclosed