Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | IL2 | P60568 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10837608 | 0.85 | KDM4E (0.56) | HRH3CYP2D6KDM4ELMNAHTT | |
| SCHEMBL342910 | 0.85 | KDM4E (0.59) | HRH3CYP2D6KDM4ELMNAHTT | |
| Hydrochloric Acid SCHEMBL11553058 | 0.83 | KDM4E (0.58) | HRH3CYP2D6KDM4ELMNAHTT | |
| SCHEMBL471858 | 0.83 | KDM4E (0.60) | HRH3CYP2D6KDM4ELMNAHTT | |
| SCHEMBL668560 | 0.82 | HRH3 (0.58) | HRH3CYP2D6KDM4ELMNAHTT | |
| Hydrochloric Acid SCHEMBL4777694 | 0.82 | KDM4E (0.56) | HRH3CYP2D6KDM4ELMNAHTT | |
| Hydrochloric Acid SCHEMBL4777692 | 0.82 | KDM4E (0.56) | HRH3CYP2D6KDM4ELMNAHTT | |
| SCHEMBL2088411 | 0.81 | HRH3 (0.55) | HRH3CYP2D6KDM4ELMNAMAPT | |
| SCHEMBL6249892 | 0.81 | HRH3 (0.52) | HRH3CYP2D6KDM4ELMNAHTT | |
| SCHEMBL20410717 | 0.81 | KDM4E (0.51) | HRH3CYP2D6KDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741044-B2 | Libraries of oligomers labeled with different tags | OXFORD GENE TECHNOLOGY IP LIMITED | 2010-06-22 | — | — | US | disclosed |
| US-20090029866-A1 | Libraries of oligomers labeled with different tags | OXFORD GENE TECHNOLOGY IP LIMITED | 2009-01-29 | — | — | US | disclosed |
| US-7399846-B2 | Libraries of oligomers labeled with different tags | OXFORD GENE TECHNOLOGY IP LIMITED (GB) | 2008-07-15 | — | — | US | disclosed |
| US-20050003408-A1 | Libraries of oligomers labeled with different tags | ISIS INNOVATION LIMITED (GB) | 2005-01-06 | — | — | US | disclosed |
| US-6780981-B1 | MAKING A SET OF LABELLED COMPOUNDS BY THE USE OF PARTICULATE SUPPORT, COMPRISES DIVIDING THE SUPPORT INTO LOTS, PERFORMING A DIFFERENT CHEMICAL REACTION ON EACH LOT OF THE SUPPORT | OXFORD GENE TECHNOLOGY IP LIMITED (GB) | 2004-08-24 | — | — | US | disclosed |
| EP-1428810-A2 | Libraries of oligomers labelled with different tags | Oxford Gene Technology IP Limited (GB) | 2004-06-16 | — | — | EP | disclosed |
| EP-1068216-B1 | LIBRARIES OF OLIGOMERS LABELLED WITH DIFFERENT TAGS | ISIS INNOVATION (GB) | 2003-12-10 | — | — | EP | disclosed |
| EP-1068216-A2 | LIBRARIES OF OLIGOMERS LABELLED WITH DIFFERENT TAGS | ISIS INNOVATION LIMITED (GB) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999060007-A2 | LIBRARIES OF OLIGOMERS LABELLED WITH DIFFERENT TAGS | ISIS INNOVATION LIMITED (GB) | 1999-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029866-A1 | Libraries of oligomers labeled with different tags | FBL, HNRNPL, MTREX | HRH3 3048/4885CYP2D6 4687/4885KDM4E 2737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.