MTREX — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Cediranib (SCHEMBL63147)	1.00	1/20
SCHEMBL1685423	0.98	1/20
SCHEMBL20077514	0.89	1/20
Cediranib (SCHEMBL4186434)	0.89	1/20
SCHEMBL1401668	0.89	1/20
SCHEMBL3198096	0.89	1/20
SCHEMBL13471998	0.89	1/20
SCHEMBL1401641	0.88	1/20
SCHEMBL14421787	0.88	1/20
Cediranib (SCHEMBL1218427)	0.87	1/20
Cediranib (SCHEMBL1218429)	0.87	1/20
SCHEMBL19668834	0.86	1/20
SCHEMBL11953084	0.84	1/20
SCHEMBL1401636	0.84	1/20
SCHEMBL11953081	0.83	1/20
SCHEMBL1401685	0.82	1/20
SCHEMBL1401791	0.81	1/20
SCHEMBL297569	0.81	1/20
SCHEMBL1401637	0.81	1/20
SCHEMBL1401646	0.81	1/20

Clinical trials — most relevant to MTREX by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
University of California, San Diego (UCSD) Suramin Autism Treatment-1 (SAT1) Trial	PHASE1/PHASE2	COMPLETED
Reverse Transcriptase Inhibitors in AGS	PHASE2	COMPLETED
Mitigating Mitochondrial RNA Release During Aging to Control Inflammation and Senescence	nan	NOT_YET_RECRUITING
B3 for NMD: Bench to Bedside and Back	nan	ENROLLING_BY_INVITATION
Cell Free Circulating Nucleic Acids as New Tumor Diagnostics From Human Plasma Samples.	nan	UNKNOWN
Micro RNA Levels in NAFLD	nan	UNKNOWN
Study of Individuals and Families With Aberrations in DDX41 or Similar Cancer Predisposition Variants	nan	RECRUITING
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve	nan	UNKNOWN
A Study That Collects Participant Data and Biospecimens to Analyze Pathogenic Exosomes That Mediate Increased Vascular Dementia Risk in Individuals With Herpes Zoster.	nan	RECRUITING
Exome Analysis in Hearing Impaired Patients	nan	UNKNOWN
Measuring Protein Turnover in Humans Across the Lifespan by Metabolic Labeling With Deuterium Oxide	nan	RECRUITING
Study of Exosomes in Monitoring Patients With Sarcoma (EXOSARC)	nan	COMPLETED
Clinical Manifestations and Biomarkers in Amyotrophic Lateral Sclerosis Type 4 and Other Inherited Neurological Disorders of RNA Processing	nan	RECRUITING
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia	nan	NOT_YET_RECRUITING
New Biomarkers in Pancreatic Cancer Using EXPEL Concept	nan	RECRUITING
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes	nan	NOT_YET_RECRUITING
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip	nan	COMPLETED
Exosomal microRNAs as a Biomarker in Panic Disorder and in Response to CBT	nan	UNKNOWN
Expression and Clinical Significance of IGHD in Pancreatic Cancer	nan	UNKNOWN
Diagnostic and Prognostic Value of MicroRNA in Breast Cancer Patients	nan	UNKNOWN
Transgenerational Metabolic-Immune Biomarkers of Neurological and Neurodevelopmental Disorders	nan	RECRUITING
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy	nan	UNKNOWN
The Natural History of Mitochondrial Diseases	nan	RECRUITING
Impact Of Choline in Patients With NAFLD	nan	UNKNOWN
Relationship Between Mitochondrial Dysfunction and Fatique in Cancer Patients Following External Beam Radiation Therapy	nan	COMPLETED
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population	nan	COMPLETED
Precision Genomics Medicine Biobank	nan	RECRUITING
Collection of Samples of Bone Marrow Aspiration From Patients With Myelodysplastic Syndrome	nan	ACTIVE_NOT_RECRUITING
Genetic Investigation of Cancer Predisposition	nan	NOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a MTREX binder may also engage these)

Protein	Name	Similarity
Q9CZU3	—	1.000	Q9CZU3 →
P47047	—	0.990	P47047 →
Q9ZVW2	—	0.990	Q9ZVW2 →
Q9XIF2	—	0.989	Q9XIF2 →
A0A0J9WQL2	—	0.988	A0A0J9WQL2 →
Q9VUV9	—	0.987	Q9VUV9 →
O14232	—	0.986	O14232 →
P24785	—	0.986	P24785 →
Q295E6	—	0.986	Q295E6 →
Q8IYB8	—	0.985	Q8IYB8 →
Q9VN03	—	0.985	Q9VN03 →
Q23223	—	0.984	Q23223 →
Q60HG1	—	0.984	Q60HG1 →
NAT10	RNA cytidine acetyltransferase	0.984	landscape →
J4KQ31	—	0.983	J4KQ31 →
Q4G005	—	0.983	Q4G005 →
Q9U2G0	—	0.983	Q9U2G0 →
Q9SYP1	—	0.983	Q9SYP1 →
Q9UJA3	—	0.983	Q9UJA3 →
A4IG62	—	0.982	A4IG62 →
Q1RMT1	—	0.982	Q1RMT1 →
Q9FUG4	—	0.982	Q9FUG4 →
Q38861	—	0.982	Q38861 →
P49135	—	0.982	P49135 →
P54358	—	0.981	P54358 →
Q803R5	—	0.981	Q803R5 →
Q80YD1	—	0.981	Q80YD1 →
Q5RA62	—	0.981	Q5RA62 →
Q5F310	—	0.981	Q5F310 →
Q8N1G2	—	0.980	Q8N1G2 →