⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL869551 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL5089741 | 0.78 | — | — | |
| SCHEMBL19328568 | 0.78 | — | — | |
| SCHEMBL9159210 | 0.77 | — | — | |
| SCHEMBL11526174 | 0.76 | — | — | |
| SCHEMBL9555610 | 0.76 | — | — | |
| SCHEMBL10589226 | 0.71 | — | — | |
| SCHEMBL2831185 | 0.68 | TRPA1 (0.31) | — | |
| SCHEMBL19664494 | 0.66 | TRPA1 (0.37) | — | |
| SCHEMBL8907428 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118660885-A | Norbornene analogs and their use as potentiators of antitubercular drugs | 国家医疗保健研究所 | 2024-09-17 | — | — | CN | claimed |
| CN-118660885-A | Norbornene analogs and their use as potentiators of antitubercular drugs | 国家医疗保健研究所 | 2024-09-17 | — | — | CN | disclosed |
| CN-117607317-B | Method for measuring depression drug in human blood plasma | 上海市民政第三精神卫生中心 | 2024-04-26 | — | — | CN | disclosed |
| CN-117607317-A | Method for measuring depression drug in human blood plasma | 上海市民政第三精神卫生中心 | 2024-02-27 | — | — | CN | disclosed |
| CN-115016230-A | Composition for forming silicon-containing resist underlayer film | 日产化学工业株式会社 | 2022-09-06 | — | — | CN | disclosed |
| EP-3256508-A1 | PROCESS FOR THE SYNTHESIS OF POLYOXAZOLIDINONE COMPOUNDS WITH HIGH STABILITY | Covestro Deutschland AG (DE) | 2017-12-20 | — | — | EP | disclosed |
| WO-2016128380-A1 | PROCESS FOR THE SYNTHESIS OF POLYOXAZOLIDINONE COMPOUNDS WITH HIGH STABILITY | COVESTRO DEUTSCHLAND AG (DE) | 2016-08-18 | — | — | WO | disclosed |
| US-9290529-B2 | Carbonic anhydrase inhibitors and method of their production | USTAV ORGANICKE CHEMIE A BIOCHEMIE AKADEMIE VED CESKE REPUBLIKY, V.V.I. (CZ) | 2016-03-22 | — | — | US | disclosed |
| EP-2771015-B1 | CARBONIC ANHYDRASE INHIBITORS AND METHOD OF THEIR PRODUCTION | ÚSTAV ORGANICKÉ CHEMIE A BIOCHEMIE AKADEMIE VED CESKÉ REPUBLIKY V V I (CZ) | 2016-03-16 | — | — | EP | disclosed |
| US-20140303390-A1 | CARBONIC ANHYDRASE INHIBITORS AND METHOD OF THEIR PRODUCTION | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2014-10-09 | — | — | US | disclosed |
| EP-2771015-A1 | CARBONIC ANHYDRASE INHIBITORS AND METHOD OF THEIR PRODUCTION | Ústav Organické Chemie A Biochemie Akademie Ved Ceské Republiky, v.v.i. (CZ) | 2014-09-03 | — | — | EP | disclosed |
| EP-2593425-A1 | THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHOD OF USE | Agios Pharmaceuticals, Inc. (US) | 2013-05-22 | — | — | EP | disclosed |
| WO-2013060307-A1 | CARBONIC ANHYDRASE INHIBITORS AND METHOD OF THEIR PRODUCTION | USTAV ORGANICKE CHEMIE A BIOCHEMIE AKADEMIE VED CESKE REPUBLIKY, V.V.I. (CZ) | 2013-05-02 | — | — | WO | disclosed |
| WO-2012009678-A1 | THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHOD OF USE | AGIOS PHARMACEUTICALS, INC. (US) | 2012-01-19 | — | — | WO | disclosed |
| US-4556651-A | Secalonic acid derivatives as antitumor agents | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-12-03 | — | — | US | disclosed |
| EP-0064199-B1 | NOVEL SECALONIC ACID DERIVATIVES AND METHOD FOR PREPARING THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1985-08-21 | — | — | EP | disclosed |
| US-4418061-A | ANTITUMOR AGENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1983-11-29 | — | — | US | disclosed |
| EP-0064199-A1 | Novel secalonic acid derivatives and method for preparing thereof | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1982-11-10 | — | — | EP | disclosed |