Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15012324 | 1.00 | LMNA (0.59) | LMNAMAPTRAB9AMEN1HPGD | |
| SCHEMBL8744479 | 1.00 | LMNA (0.59) | LMNAMAPTRAB9AMEN1HPGD | |
| SCHEMBL3614146 | 1.00 | LMNA (0.59) | LMNAMAPTRAB9AMEN1HPGD | |
| SCHEMBL15012754 | 1.00 | LMNA (0.59) | LMNAMAPTRAB9AMEN1HPGD | |
| SCHEMBL8623494 | 1.00 | LMNA (0.59) | LMNAMAPTRAB9AMEN1HPGD | |
| SCHEMBL3617109 | 1.00 | LMNA (0.59) | LMNAMAPTRAB9AMEN1HPGD | |
| SCHEMBL15012239 | 1.00 | LMNA (0.59) | LMNAMAPTRAB9AMEN1HPGD | |
| SCHEMBL3617776 | 1.00 | LMNA (0.59) | LMNAMAPTRAB9AMEN1HPGD | |
| SCHEMBL8887250 | 1.00 | LMNA (0.59) | LMNAMAPTRAB9AMEN1HPGD | |
| SCHEMBL15012405 | 1.00 | LMNA (0.59) | LMNAMAPTRAB9AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100221315-A1 | VESICULAR FORMULATIONS CONTAINING ORGANIC ACID PRODRUGS, PROCESS FOR THEIR PREPARATION | UNIVERSIDADE DE LISBOA (PT) | 2010-09-02 | — | — | US | claimed |
| EP-2034962-A2 | VESICULAR FORMULATIONS CONTAINING ORGANIC ACID PRODRUGS AND PROCESS FOR THEIR PREPARATION. | Universidade de Lisboa (PT) | 2009-03-18 | — | — | EP | claimed |
| WO-2007142548-A2 | VESICULAR FORMULATIONS CONTAINING ORGANIC ACID PRODRUGS, PROCESS FOR THEIR PREPARATION | UNIVERSIDADE DE LISBOA (PT) | 2007-12-13 | — | — | WO | claimed |
| US-20100221315-A1 | VESICULAR FORMULATIONS CONTAINING ORGANIC ACID PRODRUGS, PROCESS FOR THEIR PREPARATION | UNIVERSIDADE DE LISBOA (PT) | 2010-09-02 | — | — | US | disclosed |
| EP-2034962-A2 | VESICULAR FORMULATIONS CONTAINING ORGANIC ACID PRODRUGS AND PROCESS FOR THEIR PREPARATION. | Universidade de Lisboa (PT) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007142548-A2 | VESICULAR FORMULATIONS CONTAINING ORGANIC ACID PRODRUGS, PROCESS FOR THEIR PREPARATION | UNIVERSIDADE DE LISBOA (PT) | 2007-12-13 | — | — | WO | disclosed |