Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.36 |
| ▸ | MTOR | P42345 | 7/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 3/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
| ▸ | FKBP1B | P68106 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4203330 | 0.90 | KCNH2 (0.36) | KCNH2MTORTOP2AKDM1AFKBP1A | |
| SCHEMBL3607054 | 0.82 | KDM1A (0.32) | KDM1A | |
| SCHEMBL2822698 | 0.82 | MTOR (0.37) | KCNH2MTORTOP2AFKBP1AFKBP1B | |
| Hydrochloric Acid SCHEMBL3611488 | 0.81 | KCNH2 (0.38) | KCNH2MTORTOP2AFKBP1AFKBP1B | |
| Hydrochloric Acid SCHEMBL3611995 | 0.81 | KCNH2 (0.37) | KCNH2MTORTOP2AFKBP1AFKBP1B | |
| Hydrochloric Acid SCHEMBL3607827 | 0.81 | KCNH2 (0.38) | KCNH2MTORTOP2AFKBP1AFKBP1B | |
| Trifluoroacetic Acid SCHEMBL3611349 | 0.81 | DPP4 (0.37) | KCNH2DPP4 | |
| SCHEMBL3617948 | 0.81 | MTOR (0.32) | KCNH2MTOR | |
| SCHEMBL3602018 | 0.80 | KCNH2 (0.30) | KCNH2 | |
| SCHEMBL3611350 | 0.80 | DPP4 (0.32) | KCNH2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087424-A1 | TRICYCLIC NITROGEN CONTAINING HETEROCYCLES AS ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED | 2010-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087424-A1 | TRICYCLIC NITROGEN CONTAINING HETEROCYCLES AS ANTIBACTERIAL AGENTS | NRDC, NDC1, NANS | KCNH2 2914/4885MTOR 94/4885TOP2A 78/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.