Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4212847 | 0.89 | KDM1A (0.32) | KDM1AMAPK1 | |
| Hydrochloric Acid SCHEMBL4367609 | 0.88 | KDM1A (0.32) | KDM1AMAPK1 | |
| SCHEMBL3607906 | 0.83 | CHRM1 (0.38) | — | |
| SCHEMBL3612945 | 0.82 | KCNH2 (0.36) | KDM1A | |
| SCHEMBL3615776 | 0.81 | CNR1 (0.30) | — | |
| SCHEMBL3604795 | 0.79 | CDK4 (0.37) | — | |
| SCHEMBL3616104 | 0.73 | KCNH2 (0.57) | — | |
| SCHEMBL2819511 | 0.73 | SIGMAR1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL3612654 | 0.72 | KCNH2 (0.57) | — | |
| SCHEMBL3605732 | 0.72 | KCNH2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087424-A1 | TRICYCLIC NITROGEN CONTAINING HETEROCYCLES AS ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED | 2010-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087424-A1 | TRICYCLIC NITROGEN CONTAINING HETEROCYCLES AS ANTIBACTERIAL AGENTS | NRDC, NDC1, NANS | KDM1A 4178/4885MAPK1 3098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.