Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 9/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.39 |
| ▸ | NQO2 | P16083 | 6/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3605593 | 0.97 | NAMPT (0.39) | NPC1RAB9AMTNR1AMTNR1BNQO2 | |
| SCHEMBL14153341 | 0.84 | NPC1 (0.42) | NPC1RAB9AMTNR1AMTNR1BNQO2 | |
| SCHEMBL14153345 | 0.81 | NAMPT (0.40) | NPC1RAB9AMTNR1AMTNR1BNQO2 | |
| SCHEMBL3611654 | 0.79 | NPC1 (0.41) | NPC1RAB9AHDAC1HDAC8SMN1; SMN2 | |
| SCHEMBL3609220 | 0.78 | KMT2A (0.39) | NPC1RAB9AHDAC1HDAC8CYP2D6 | |
| SCHEMBL3611740 | 0.77 | HDAC1 (0.39) | NPC1RAB9AMTNR1AMTNR1BNQO2 | |
| SCHEMBL7740161 | 0.72 | CA1 (0.55) | HDAC1HDAC8HPGDCYP2D6MAPT | |
| SCHEMBL1764094 | 0.71 | CA1 (0.45) | HDAC1HDAC8HPGDCYP2D6MAPT | |
| SCHEMBL14023026 | 0.71 | CA1 (0.45) | HDAC1HDAC8HPGDCYP2D6MAPT | |
| SCHEMBL766395 | 0.70 | CA1 (0.44) | HDAC1HDAC8HPGDCYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741044-B2 | Libraries of oligomers labeled with different tags | OXFORD GENE TECHNOLOGY IP LIMITED | 2010-06-22 | — | — | US | disclosed |
| US-20090029866-A1 | Libraries of oligomers labeled with different tags | OXFORD GENE TECHNOLOGY IP LIMITED | 2009-01-29 | — | — | US | disclosed |
| US-7399846-B2 | Libraries of oligomers labeled with different tags | OXFORD GENE TECHNOLOGY IP LIMITED (GB) | 2008-07-15 | — | — | US | disclosed |
| US-20050003408-A1 | Libraries of oligomers labeled with different tags | ISIS INNOVATION LIMITED (GB) | 2005-01-06 | — | — | US | disclosed |
| US-6780981-B1 | MAKING A SET OF LABELLED COMPOUNDS BY THE USE OF PARTICULATE SUPPORT, COMPRISES DIVIDING THE SUPPORT INTO LOTS, PERFORMING A DIFFERENT CHEMICAL REACTION ON EACH LOT OF THE SUPPORT | OXFORD GENE TECHNOLOGY IP LIMITED (GB) | 2004-08-24 | — | — | US | disclosed |
| EP-1428810-A2 | Libraries of oligomers labelled with different tags | Oxford Gene Technology IP Limited (GB) | 2004-06-16 | — | — | EP | disclosed |
| EP-1068216-B1 | LIBRARIES OF OLIGOMERS LABELLED WITH DIFFERENT TAGS | ISIS INNOVATION (GB) | 2003-12-10 | — | — | EP | disclosed |
| EP-1068216-A2 | LIBRARIES OF OLIGOMERS LABELLED WITH DIFFERENT TAGS | ISIS INNOVATION LIMITED (GB) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999060007-A2 | LIBRARIES OF OLIGOMERS LABELLED WITH DIFFERENT TAGS | ISIS INNOVATION LIMITED (GB) | 1999-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029866-A1 | Libraries of oligomers labeled with different tags | FBL, HNRNPL, MTREX | NPC1 3673/4885RAB9A 3491/4885MTNR1A 4187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.