Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SCD | O00767 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL920818 | 0.86 | NPC1 (0.48) | RAB9ANPC1SMN1; SMN2HTTDYRK1A | |
| SCHEMBL31540156 | 0.86 | NPC1 (0.48) | RAB9ANPC1SMN1; SMN2HTTDYRK1A | |
| SCHEMBL3618377 | 0.85 | PIK3CA (0.49) | RAB9ANPC1SMN1; SMN2CYP3A4KMT2A | |
| SCHEMBL7104770 | 0.84 | TP53 (0.67) | RAB9ANPC1SMN1; SMN2DYRK1AKMT2A | |
| SCHEMBL14611315 | 0.82 | DYRK1A (0.57) | RAB9ANPC1SMN1; SMN2HTTCYP1A2 | |
| SCHEMBL3612693 | 0.81 | APP (0.53) | RAB9ANPC1SMN1; SMN2HTTCYP1A2 | |
| SCHEMBL8536132 | 0.81 | APP (0.63) | RAB9ACYP1A2CYP3A4CYP2C19KMT2A | |
| SCHEMBL11972685 | 0.80 | APP (0.58) | RAB9AKMT2AMEN1GAAAPP | |
| SCHEMBL1983051 | 0.80 | APP (0.58) | RAB9AKMT2AMEN1GAAAPP | |
| SCHEMBL8784838 | 0.79 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9468694-B2 | Fluorination process | GE HEALTHCARE LIMITED (GB) | 2016-10-18 | — | — | US | disclosed |
| US-9468694-B2 | Fluorination process | GE HEALTHCARE LIMITED (GB) | 2016-10-18 | — | — | US | disclosed |
| US-20150328344-A1 | Fluorination Process | GE HEALTHCARE AS (NO) | 2015-11-19 | — | — | US | disclosed |
| US-20150328344-A1 | Fluorination Process | GE HEALTHCARE AS (NO) | 2015-11-19 | — | — | US | disclosed |
| CN-102731432-B | The fluorination process of anilid derivative and the benzothiazole fluorinated derivatives as in-vivo imaging agent | GE HEALTHCARE LTD. (GB) | 2015-10-21 | — | — | CN | disclosed |
| US-9126961-B2 | Fluorination process | GE HEALTHCARE LIMITED (GB) | 2015-09-08 | — | — | US | disclosed |
| US-9126961-B2 | Fluorination process | GE HEALTHCARE LIMITED (GB) | 2015-09-08 | — | — | US | disclosed |
| EP-1915330-B1 | FLUORINATION PROCESS OF ANILIDE DERIVATIVES AND BENZOTHIAZOLE FLUORINATE DERIVATIVES AS IN VIVO IMAGING AGENTS | GE HEALTHCARE LTD (GB) | 2014-12-10 | — | — | EP | disclosed |
| CN-101282920-B | Method for fluorination of anilide derivatives and benzothiazole fluorinated derivatives as in vivo imaging agents | GE HEALTHCARE LTD | 2014-06-04 | — | — | CN | disclosed |
| US-20130225829-A1 | FLUORINATION PROCESS | GE HEALTHCARE AS (NO) | 2013-08-29 | — | — | US | disclosed |
| US-20130225829-A1 | FLUORINATION PROCESS | GE HEALTHCARE AS (NO) | 2013-08-29 | — | — | US | disclosed |
| US-8410312-B2 | Fluorination process of anilide derivatives and benzothiazole fluorinate derivatives as in vivo imaging agents | GE HEALTHCARE LIMITED (GB) | 2013-04-02 | — | — | US | disclosed |
| US-8410312-B2 | Fluorination process of anilide derivatives and benzothiazole fluorinate derivatives as in vivo imaging agents | GE HEALTHCARE LIMITED (GB) | 2013-04-02 | — | — | US | disclosed |
| US-8410312-B2 | Fluorination process of anilide derivatives and benzothiazole fluorinate derivatives as in vivo imaging agents | GE HEALTHCARE LIMITED (GB) | 2013-04-02 | — | — | US | disclosed |
| US-20100234611-A1 | Fluorination Process of Anilide Derivatives and Benzothiazole Fluorinate Derivatives as in VIVO Imaging Agents | GE HEALTHCARE LIMITED (GB) | 2010-09-16 | — | — | US | disclosed |
| US-20100234611-A1 | Fluorination Process of Anilide Derivatives and Benzothiazole Fluorinate Derivatives as in VIVO Imaging Agents | GE HEALTHCARE LIMITED (GB) | 2010-09-16 | — | — | US | disclosed |
| US-20100234611-A1 | Fluorination Process of Anilide Derivatives and Benzothiazole Fluorinate Derivatives as in VIVO Imaging Agents | GE HEALTHCARE LIMITED (GB) | 2010-09-16 | — | — | US | disclosed |
| EP-1915330-A1 | FLUORINATION PROCESS OF ANILIDE DERIVATIVES AND BENZOTHIAZOLE FLUORINATE DERIVATIVES AS IN VIVO IMAGING AGENTS | GE Healthcare Limited (GB) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007020400-A1 | FLUORINATION PROCESS OF ANILIDE DERIVATIVES AND BENZOTHIAZOLE FLUORINATE DERIVATIVES AS IN VIVO IMAGING AGENTS | GE HEALTHCARE LIMITED (GB) | 2007-02-22 | — | — | WO | disclosed |
| WO-2007020400-A1 | FLUORINATION PROCESS OF ANILIDE DERIVATIVES AND BENZOTHIAZOLE FLUORINATE DERIVATIVES AS IN VIVO IMAGING AGENTS | GE HEALTHCARE LIMITED (GB) | 2007-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150328344-A1 | Fluorination Process | CYP2F1, C1R, C1S | RAB9A 25/4885NPC1 351/4885SMN1; SMN2 4627/4885 |
| US-20100234611-A1 | Fluorination Process of Anilide Derivatives and Benzothiazole Fluorinate Derivatives as in VIVO Imaging Agents | Q6ZSR9, AFF1, F9 | RAB9A 45/4885NPC1 1014/4885SMN1; SMN2 4448/4885 |
| US-20130225829-A1 | FLUORINATION PROCESS | CYP2F1, C1R, C1S | RAB9A 25/4885NPC1 351/4885SMN1; SMN2 4627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.