Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 7/20 | 0.36 |
| ▸ | CES2 | O00748 | 6/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9323454 | 0.79 | FFAR3 (0.48) | MEN1KMT2ACES1CES2FFAR3 | |
| SCHEMBL11251695 | 0.77 | CES1 (0.36) | CES1CES2FFAR3HDAC3HDAC1 | |
| SCHEMBL4733808 | 0.77 | FAAH (0.55) | SOAT1MEN1FAAHTP53CYP1A2 | |
| SCHEMBL4782314 | 0.77 | FAAH (0.55) | SOAT1MEN1FAAHTP53CYP1A2 | |
| SCHEMBL197237 | 0.74 | — | — | |
| SCHEMBL8310114 | 0.73 | — | — | |
| SCHEMBL19994140 | 0.72 | — | — | |
| SCHEMBL11468194 | 0.71 | TDP1 (0.39) | CES1CES2KDM4ECA1 | |
| SCHEMBL11251711 | 0.70 | — | — | |
| Butyramide SCHEMBL5681 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593424-A1 | NOVEL ARYLAMIDE DERIVATIVES HAVING ANTIANDROGENIC PROPERTIES | Medeia Therapeutics Ltd (FI) | 2013-05-22 | — | — | EP | claimed |
| WO-2012007644-A1 | NOVEL ARYLAMIDE DERIVATIVES HAVING ANTIANDROGENIC PROPERTIES | MEDEIA THERAPEUTICS LTD (FI) | 2012-01-19 | — | — | WO | claimed |
| EP-2593424-A1 | NOVEL ARYLAMIDE DERIVATIVES HAVING ANTIANDROGENIC PROPERTIES | Medeia Therapeutics Ltd (FI) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007644-A1 | NOVEL ARYLAMIDE DERIVATIVES HAVING ANTIANDROGENIC PROPERTIES | MEDEIA THERAPEUTICS LTD (FI) | 2012-01-19 | — | — | WO | disclosed |