⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23494298 | 0.83 | — | — | |
| SCHEMBL8050995 | 0.75 | — | — | |
| SCHEMBL20446697 | 0.72 | — | — | |
| SCHEMBL17634027 | 0.70 | — | — | |
| SCHEMBL4819466 | 0.70 | — | — | |
| SCHEMBL21088951 | 0.70 | — | — | |
| SCHEMBL56901 | 0.70 | — | — | |
| SCHEMBL910278 | 0.70 | — | — | |
| SCHEMBL13697555 | 0.69 | ALDH1A1 (0.42) | — | |
| SCHEMBL21859114 | 0.69 | IDO1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662849-B2 | Amidino compounds as cysteine protease inhibitors | VIROBAY, INC. (US) | 2010-02-16 | — | — | US | claimed |
| US-20070276019-A1 | Haloalkyl Containing Compounds as Cysteine Protease Inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2007-11-29 | — | — | US | claimed |
| EP-1761485-A1 | AMIDINO COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | Schering AG (DE) | 2007-03-14 | — | — | EP | claimed |
| JP-2006526657-A | — | — | 2006-11-24 | — | — | JP | claimed |
| US-20060264464-A1 | Amidino compounds as cysteine protease inhibitors | QUEST DIAGNOSTICS INVESTMENTS LLC | 2006-11-23 | — | — | US | claimed |
| WO-2004108661-A1 | AMIDINO COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS (US) | 2004-12-16 | — | — | WO | claimed |
| US-5843950-A | 1,4-dihydropyridine compound and pharmaceutical composition containing the same | NIKKEN CHEMICALS CO., LTD. (JP) | 1998-12-01 | — | — | US | claimed |
| EP-0801065-A1 | 1,4-DIHYDROPYRIDINE COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1997-10-15 | — | — | EP | claimed |
| CN-105636965-B | The ring type compound of sulfur-bearing two | 安斯泰来制药株式会社 | 2017-11-24 | — | — | CN | disclosed |
| CN-102884034-B | Compound with wood fragrance | MANE FILS V | 2014-08-13 | — | — | CN | disclosed |
| CN-102884034-A | Compound with wood fragrance | MANE FILS V | 2013-01-16 | — | — | CN | disclosed |
| US-7662849-B2 | Amidino compounds as cysteine protease inhibitors | VIROBAY, INC. (US) | 2010-02-16 | — | — | US | disclosed |
| US-20070276019-A1 | Haloalkyl Containing Compounds as Cysteine Protease Inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2007-11-29 | — | — | US | disclosed |
| US-20060264464-A1 | Amidino compounds as cysteine protease inhibitors | QUEST DIAGNOSTICS INVESTMENTS LLC | 2006-11-23 | — | — | US | disclosed |
| US-5714611-A | REACTING TETRAMETHYLPIPERIDINYL COMPOUNDS WITH A CYCLIC CARBONATE SELECTED FROM CYCLIC ETHYLENE CARBONATE OR PROPYLENE CARBONATE/1,3-/ IN PRESENCE OF AN ACID CATALYST | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-03 | — | — | US | disclosed |
| EP-0801065-A1 | 1,4-DIHYDROPYRIDINE COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1997-10-15 | — | — | EP | disclosed |
| CN-1139921-A | Process for producing N,N'-bridged bis-tetramethyl piperidinyl compounds | BASF AG (DE) | 1997-01-08 | — | — | CN | disclosed |
| EP-0741703-A1 | PROCESS FOR PRODUCING N,N'-BRIDGED BIS-TETRAMETHYL PIPERIDINYL COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 1996-11-13 | — | — | EP | disclosed |
| WO-1995021157-A1 | PROCESS FOR PRODUCING N,N'-BRIDGED BIS-TETRAMETHYL PIPERIDINYL COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 1995-08-10 | — | — | WO | disclosed |
| US-4593090-A | Containing perhydrofuran or pyran ring structure | GOGO KIMURA (JP) | 1986-06-03 | — | — | US | disclosed |