Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3625787 | 1.00 | DNM1 (0.57) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3626056 | 1.00 | DNM1 (0.57) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL24835048 | 1.00 | DNM1 (0.57) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3614673 | 1.00 | DNM1 (0.57) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL28512813 | 0.98 | DNM1 (0.59) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL19708567 | 0.98 | ACE2 (0.55) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL8579435 | 0.98 | DNM1 (0.59) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL13520175 | 0.97 | DNM1 (0.52) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3622910 | 0.95 | DNM1 (0.65) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL20017999 | 0.95 | DNM1 (0.65) | DNM1MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939450-A | TREATMENT OF RHEUMATIOD ARTHRITIS | ANORMED INC. (CA) | 1999-08-17 | — | — | US | claimed |
| CN-1219129-A | Use of substituted azaspiranes in the treatment of asthma | ANORMED INC (CA) | 1999-06-09 | — | — | CN | claimed |
| US-5786376-A | Methods of treating opportunistic infections with azaspiranes | SMITHKLINE BEECHAM CORPORATION (US) | 1998-07-28 | — | — | US | claimed |
| US-5744495-A | IMMUNOMODULATORY AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-04-28 | — | — | US | claimed |
| US-5734061-A | Process for preparing spirocyclic lactams | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-31 | — | — | US | claimed |
| CN-1157564-A | Method of treating opportunistic infections with azaspiranes | SMITHKLINE BEECHAM CORP (US) | 1997-08-20 | — | — | CN | claimed |
| CN-1140710-A | N,N-diethyl-8,8-dipropyl-2-azaspiro(4,5) decane-2-propanamine dimaleate | SMITHKLINE BEECHAM CORP (US) | 1997-01-22 | — | — | CN | claimed |
| CN-1130873-A | Method of treating HIV with azaspiranes | SMITHKLINE BEECHAM CORP (US) | 1996-09-11 | — | — | CN | claimed |
| CN-1130871-A | Method of inhibiting replication of human immunodeficiency viruses with substituted azaspiranes | SMITHKLINE BEECHAM CORP (US) | 1996-09-11 | — | — | CN | claimed |
| CN-1130870-A | Method of inhibiting production of human immunodeficiency viruses with substituted azaspiranes | SMITHKLINE BEECHAM CORP (US) | 1996-09-11 | — | — | CN | claimed |
| CN-1100932-A | Use of the substituted azaspirane in the manufacture of a medieament for the treatment of psoriasis | SMITHKLINE BEECHAM CORP (US) | 1995-04-05 | — | — | CN | claimed |
| EP-0624089-A4 | METHODS. | — | 1994-12-14 | — | — | EP | claimed |
| EP-0624089-A1 | METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-11-17 | — | — | EP | claimed |
| WO-1993014760-A2 | METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-08-05 | — | — | WO | claimed |
| US-11038125-B2 | Organic semiconductor element, polymer, organic semiconductor composition, and organic semiconductor film | FUJIFILM CORPORATION (JP) | 2021-06-15 | — | — | US | disclosed |
| US-20190027696-A1 | ORGANIC SEMICONDUCTOR ELEMENT, POLYMER, ORGANIC SEMICONDUCTOR COMPOSITION, AND ORGANIC SEMICONDUCTOR FILM | FUJIFILM CORPORATION (JP) | 2019-01-24 | — | — | US | disclosed |
| CN-104174071-A | COMPOSITIONS AND SYSTEMS FOR FORMING CROSSLINKED BIOMATERIALS AND ASSOCIATED METHODS OF PREPARATION AND USE | ANGIODEVICE INTERNAT GMBH | 2014-12-03 | — | — | CN | disclosed |
| EP-0733042-A1 | PROCESS FOR PREPARING SPIROCYCLIC LACTAMS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-09-25 | — | — | EP | disclosed |
| EP-0733042-A4 | PROCESS FOR PREPARING SPIROCYCLIC LACTAMS | SMITHKLINE BEECHAM CORP (US) | 1996-07-30 | — | — | EP | disclosed |
| WO-1995016657-A1 | PROCESS FOR PREPARING SPIROCYCLIC LACTAMS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-06-22 | — | — | WO | disclosed |