Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 11/20 | 0.63 |
| ▸ | MAOB | P27338 | 10/20 | 0.63 |
| ▸ | HTR2B | P41595 | 6/20 | 0.63 |
| ▸ | HTR2A | P28223 | 4/20 | 0.63 |
| ▸ | MAOA | P21397 | 7/20 | 0.48 |
| ▸ | KDM1A | O60341 | 5/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16388354 | 1.00 | HTR2C (0.63) | HTR2CMAOBHTR2BHTR2AMAOA | |
| SCHEMBL3614739 | 1.00 | HTR2C (0.63) | HTR2CMAOBHTR2BHTR2AMAOA | |
| SCHEMBL3614757 | 1.00 | HTR2C (0.63) | HTR2CMAOBHTR2BHTR2AMAOA | |
| SCHEMBL20208616 | 0.88 | KDM1A (0.55) | HTR2CMAOBHTR2BHTR2AKDM1A | |
| SCHEMBL21480337 | 0.88 | KDM1A (0.55) | HTR2CMAOBHTR2BHTR2AKDM1A | |
| SCHEMBL23562775 | 0.77 | HTR2C (0.63) | HTR2CMAOBHTR2BHTR2AMAOA | |
| SCHEMBL6585775 | 0.77 | HTR2C (0.63) | HTR2CMAOBHTR2BHTR2AMAOA | |
| SCHEMBL4129782 | 0.77 | HTR2C (1.00) | HTR2CMAOBHTR2BHTR2ASLC6A2 | |
| SCHEMBL4144327 | 0.77 | HTR2C (1.00) | HTR2CMAOBHTR2BHTR2ASLC6A2 | |
| SCHEMBL9043644 | 0.77 | HTR2C (0.63) | HTR2CMAOBHTR2BHTR2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9695154-B2 | Heteroaryl inhibitors of sumo activating enzyme | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-9695154-B2 | Heteroaryl inhibitors of sumo activating enzyme | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-20160355504-A1 | HETEROARYL INHIBITORS OF SUMO ACTIVATING ENZYME | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2016-12-08 | — | — | US | disclosed |
| US-20160355504-A1 | HETEROARYL INHIBITORS OF SUMO ACTIVATING ENZYME | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2016-12-08 | — | — | US | disclosed |
| WO-2015002994-A2 | HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF SUMO ACTIVATING ENZYME | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2015-01-08 | — | — | WO | disclosed |
| US-8309545-B2 | Benzofuran potassium channel blockers and uses thereof | BIONOMICS LIMITED (AU) | 2012-11-13 | — | — | US | disclosed |
| US-20100087430-A1 | NOVEL BENZOFURAN POTASSIUM CHANNEL BLOCKERS AND USES THEREOF | BIONOMICS LIMITED (AU) | 2010-04-08 | — | — | US | disclosed |
| US-7498344-B2 | Arylpiperidinol and arylpiperidine derivatives and pharmaceuticals containing the same | ASUBIO PHARMA CO., LTD. (JP) | 2009-03-03 | — | — | US | disclosed |
| US-7488738-B2 | Aminophenoxyacetic acid derivatives and pharmaceutical composition containing thereof | ASUBIO PHARMA CO., LTD. (JP) | 2009-02-10 | — | — | US | disclosed |
| WO-2008040057-A1 | NOVEL BENZOFURAN POTASSIUM CHANNEL BLOCKERS AND USES THEREOF | BIONOMICS LIMITED (AU) | 2008-04-10 | — | — | WO | disclosed |
| EP-1045693-A1 | AMINOPHENOXYACETIC ACID DERIVATIVES AS NEUROPROTECTANTS | SUNTORY LIMITED (JP) | 2000-10-25 | — | — | EP | disclosed |
| WO-2000023076-A1 | AMINOPHENOXYACETIC ACID DERIVATIVES AS NEUROPROTECTANTS | SUNTORY LIMITED (JP) | 2000-04-27 | — | — | WO | disclosed |
| US-6048876-A | ANTICONVULSANTS; ANTIEPILEPIC AGENT | SUNTORY LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0867183-A1 | ARYLPIPERIDINOL AND ARYLPIPERIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1998-09-30 | — | — | EP | disclosed |
| EP-0755923-A1 | AMELIORANT OR REMEDY FOR SYMPTOMS CAUSED BY ISCHEMIC DISEASES AND COMPOUNDS USEFUL THEREFOR | SUNTORY LIMITED (JP) | 1997-01-29 | — | — | EP | disclosed |
| EP-0445013-B1 | C-cycloalkyl-alkylamines, process for their preparation, their use as therapeutic agents and intermediates for their synthesis | JOUVEINAL SA (FR) | 1994-06-08 | — | — | EP | disclosed |
| US-5089639-A | N-CYCLOALKYLALKYLAMINES, PROCESS FOR THEIR PREPARATION, THEIR USE AS A MEDICAMENT AND THEIR SYNTHESIS INTERMEDIATES | JOUVEINAL S.A. (FR) | 1992-02-18 | — | — | US | disclosed |
| EP-0446097-A1 | Substituted etylamines, process for their preparation, their use as therapeutic agents and intermediates for their synthesis | JOUVEINAL S.A. (FR) | 1991-09-11 | — | — | EP | disclosed |
| EP-0445013-A1 | C-cycloalkyl-alkylamines, process for their preparation, their use as therapeutic agents and intermediates for their synthesis | JOUVEINAL S.A. (FR) | 1991-09-04 | — | — | EP | disclosed |
| US-5034419-A | Psychological disorders or gastrointestinal disorders | L'OREAL (FR) | 1991-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087430-A1 | NOVEL BENZOFURAN POTASSIUM CHANNEL BLOCKERS AND USES THEREOF | KCNA3, KCNB1, KCNK3 | HTR2C 4365/4885MAOB 1764/4885HTR2B 3091/4885 |
| US-20160355504-A1 | HETEROARYL INHIBITORS OF SUMO ACTIVATING ENZYME | SAE1, SUMO2, SUMO1 | HTR2C 2891/4885MAOB 1989/4885HTR2B 3027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.