SCHEMBL3619359

SCHEMBL3619359

CCc1c(CC(=O)O)c2cccnc2n1Cc1cccnc1

nearest known ligand 0.76

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 20/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1940594 0.86 PTGDR2 (1.00) PTGDR2
SCHEMBL3619352 0.84 PTGDR2 (0.66) PTGDR2
SCHEMBL1941857 0.82 PTGDR2 (0.77) PTGDR2
SCHEMBL5372499 0.81 PTGDR2 (0.78) PTGDR2
SCHEMBL1939991 0.76 PTGDR2 (1.00) PTGDR2
SCHEMBL1939808 0.75 PTGDR2 (0.78) PTGDR2
SCHEMBL1939826 0.74 PTGDR2 (1.00) PTGDR2
SCHEMBL1940106 0.72 PTGDR2 (1.00) PTGDR2
SCHEMBL1939892 0.72 PTGDR2 (0.80) PTGDR2
SCHEMBL1940145 0.71 PTGDR2 (1.00) PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7666878-B2 (1-Benzyl-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-acetic acid; chemoattractant receptor-homologous molecule expressed on helper T-cells antagonist; antiinflammatory agent, antiallergen; obstructive airways disease NOVARTIS AG (CH) 2010-02-23 US claimed