Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 18/20 | 0.66 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3619359 | 0.84 | PTGDR2 (0.76) | PTGDR2 | |
| SCHEMBL1940594 | 0.80 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL1939991 | 0.72 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL1939826 | 0.70 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL2925018 | 0.70 | PTGDR2 (0.78) | PTGDR2 | |
| SCHEMBL2925902 | 0.69 | PTGDR2 (0.76) | PTGDR2 | |
| SCHEMBL1941857 | 0.69 | PTGDR2 (0.77) | PTGDR2 | |
| SCHEMBL5372499 | 0.68 | PTGDR2 (0.78) | PTGDR2 | |
| SCHEMBL1939808 | 0.68 | PTGDR2 (0.78) | PTGDR2 | |
| Alcohol SCHEMBL28317498 | 0.68 | NAPRT (0.86) | PTGDR2NAPRTTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7666878-B2 | (1-Benzyl-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-acetic acid; chemoattractant receptor-homologous molecule expressed on helper T-cells antagonist; antiinflammatory agent, antiallergen; obstructive airways disease | NOVARTIS AG (CH) | 2010-02-23 | — | — | US | claimed |