Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1798885 | 1.00 | CA2 (0.63) | CA2MAPK1GRIK1GRIK2LCK | |
| SCHEMBL8663246 | 1.00 | CA2 (0.63) | CA2MAPK1GRIK1GRIK2LCK | |
| SCHEMBL23071374 | 1.00 | CA2 (0.63) | CA2MAPK1GRIK1GRIK2LCK | |
| SCHEMBL284756 | 0.98 | CA2 (0.65) | CA2MAPK1GRIK1GRIK2LCK | |
| SCHEMBL1554383 | 0.91 | CA2 (0.68) | CA2MAPK1GRIK1GRIK2LCK | |
| SCHEMBL14359878 | 0.89 | CA2 (0.77) | CA2MAPK1GRIK1GRIK2LCK | |
| SCHEMBL27901184 | 0.89 | CA2 (0.77) | CA2MAPK1GRIK1GRIK2LCK | |
| SCHEMBL14360381 | 0.89 | CA2 (0.77) | CA2MAPK1GRIK1GRIK2LCK | |
| SCHEMBL10897254 | 0.87 | CA2 (0.81) | CA2MAPK1GRIK1GRIK2SLC1A2 | |
| SCHEMBL18641746 | 0.86 | GRIK1 (0.58) | CA2MAPK1GRIK1GRIK2LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088536-A | ALKYLATING LITHIUM CYCLOPENTADIENE, OXYGENATING TO PRODUCE HYDROXYCLYCLOPENTENONES, SEPARATION, MULTISTAGE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1978-05-09 | — | — | US | claimed |
| US-4031129-A | LITHIUM CYCLOPENTADIENE, ETHYL-7-BROMOHEPTANOATE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1977-06-21 | — | — | US | claimed |
| EP-4598536-A2 | INDAZOLE PYRIDONE COMPOUNDS AND USES THEREOF | Bluejay Therapeutics, Inc. (US) | 2025-08-13 | — | — | EP | disclosed |
| US-20240182472-A1 | INDAZOLE PYRIDONE COMPOUNDS AND USES THEREOF | MIRUM PHARMACEUTICALS, INC. | 2024-06-06 | — | — | US | disclosed |
| WO-2024077024-A2 | INDAZOLE PYRIDONE COMPOUNDS AND USES THEREOF | BLUEJAY THERAPEUTICS, INC. (US) | 2024-04-11 | — | — | WO | disclosed |
| EP-2970154-B1 | TETRAHYDROXAMATE CHELATORS OF ZIRCONIUM89 AND NIOBIUM90 FOR USE IN DIAGNOSTIC APPLICATIONS | US HEALTH (US) | 2021-07-07 | — | — | EP | disclosed |
| US-10137212-B2 | Tetrahydroxamate chelators of zirconium89 and niobium90 for use in diagnostic applications | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2018-11-27 | — | — | US | disclosed |
| EP-2593452-B1 | IP RECEPTOR AGONIST HETEROCYCLIC COMPOUNDS | NOVARTIS AG (CH) | 2017-01-18 | — | — | EP | disclosed |
| US-20160022844-A1 | TETRAHYDROXAMATE CHELATORS OF ZIRCONIUM89 AND NIOBIUM90 FOR USE IN DIAGNOSTIC APPLICATIONS | The USA, as represented by the secretary, Department of Health & Human Service (US) | 2016-01-28 | — | — | US | disclosed |
| EP-2970154-A1 | TETRAHYDROXAMATE CHELATORS OF ZIRCONIUM89 AND NIOBIUM90 FOR USE IN DIAGNOSTIC APPLICATIONS | The U.S.A. As Represented By The Secretary, Department Of Health And Human Services (US) | 2016-01-20 | — | — | EP | disclosed |
| US-9132127-B2 | Substituted pyrido[2,3-B]pyrazines as IP receptor agonists | NOVARTIS AG (CH) | 2015-09-15 | — | — | US | disclosed |
| US-4177346-A | 1,5-Disubstituted-2-pyrrolidones | PFIZER INC. (US) | 1979-12-04 | — | — | US | disclosed |
| US-4155908-A | PSORIASIS, ANTICOAGULANTS | MERCK & CO., INC. (US) | 1979-05-22 | — | — | US | disclosed |
| US-4142056-A | MULTISTAGE PROCESS FOR PREPARING 2-(6'-CARBOMETHOXYHEXYL)-2-CYCLOPENTEN-1-ONE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1979-02-27 | — | — | US | disclosed |
| US-4128564-A | 9-Thia- and oxothia- and 9-dioxothia-11,12-seco-prostaglandins | MERCK & CO., INC. (US) | 1978-12-05 | — | — | US | disclosed |
| US-4088536-A | ALKYLATING LITHIUM CYCLOPENTADIENE, OXYGENATING TO PRODUCE HYDROXYCLYCLOPENTENONES, SEPARATION, MULTISTAGE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1978-05-09 | — | — | US | disclosed |
| US-4085125-A | 9-Thia-, 9-oxothia-, and 9-dioxothia-11,12-seco-prostaglandins and processes | MERCK & CO., INC. (US) | 1978-04-18 | — | — | US | disclosed |
| US-4066675-A | PSORIASIS, THROMBOSIS | MERCK & CO., INC. (US) | 1978-01-03 | — | — | US | disclosed |
| US-4031129-A | LITHIUM CYCLOPENTADIENE, ETHYL-7-BROMOHEPTANOATE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1977-06-21 | — | — | US | disclosed |
| US-4018802-A | SKIN DISEASES, GROWTH HORMONE STIMULANTS, THROMBUS PREVENTION, IMMUNOLOGY | MERCK & CO., INC. (US) | 1977-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240182472-A1 | INDAZOLE PYRIDONE COMPOUNDS AND USES THEREOF | PFKL, PNPO, CYP7A1 | CA2 4821/4885MAPK1 2554/4885GRIK1 1390/4885 |
| US-20160022844-A1 | TETRAHYDROXAMATE CHELATORS OF ZIRCONIUM89 AND NIOBIUM90 FOR USE IN DIAGNOSTIC APPLICATIONS | SLC39A3, SLC39A11, SLC39A7 | CA2 2081/4885MAPK1 4360/4885GRIK1 727/4885 |
| US-10137212-B2 | Tetrahydroxamate chelators of zirconium89 and niobium90 for use in diagnostic applications | SLC39A3, SLC39A11, SLC39A7 | CA2 2081/4885MAPK1 4360/4885GRIK1 727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.