Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961970 | 0.95 | MEN1 (0.39) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL8654494 | 0.93 | KMT2A (0.45) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL7619544 | 0.85 | KMT2A (0.43) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL6411427 | 0.84 | KMT2A (0.42) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL6916199 | 0.84 | KMT2A (0.42) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL8746193 | 0.82 | GAA (0.48) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL71839 | 0.82 | KMT2A (0.41) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL2762565 | 0.82 | KMT2A (0.41) | KMT2AMEN1ESR1ESR2GAA | |
| Hydrochloric Acid SCHEMBL27691765 | 0.82 | KMT2A (0.41) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL28577594 | 0.81 | CA12 (0.43) | KMT2AMEN1ESR1ESR2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117855603-A | Nonaqueous electrolyte, preparation method thereof and lithium ion battery | 惠州市豪鹏科技有限公司 | 2024-04-09 | — | — | CN | disclosed |
| EP-2766345-A1 | SUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUNDS AS FACTOR XIA INHIBITORS | Bristol-Myers Squibb Company (US) | 2014-08-20 | — | — | EP | disclosed |
| EP-1677822-B1 | 4'-THIONUCLEOSIDES AND OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS INC (US) | 2014-04-23 | — | — | EP | disclosed |
| WO-2013055984-A1 | SUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUNDS AS FACTOR XIA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-04-18 | — | — | WO | disclosed |
| WO-2012066065-A1 | PHENYL-HETEROARYL AMINE COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2012-05-24 | — | — | WO | disclosed |
| WO-2010090860-A2 | METHODS AND COMPOSITIONS FOR TREATING BACTERIAL INFECTION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2010-08-12 | — | — | WO | disclosed |
| EP-1677822-A4 | 4'-THIONUCLEOSIDES AND OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS INC (US) | 2009-08-19 | — | — | EP | disclosed |
| WO-2005027962-A9 | 4’-THIONUCLEOSIDES AND OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS INC (US) | 2006-08-10 | — | — | WO | disclosed |
| EP-1677822-A2 | 4'-THIONUCLEOSIDES AND OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005027962-A1 | 4’-THIONUCLEOSIDES AND OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 2005-03-31 | — | — | WO | disclosed |