SCHEMBL3620245

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL275748	0.92	FLT3 (0.42)	KDRBTKRIPK1FLT1TEK
	SCHEMBL3610110	0.89	TEK (0.47)	KDRBTKRIPK1FLT1TEK
	SCHEMBL275201	0.89	RIPK1 (0.44)	KDRBTKRIPK1FLT1TEK
	SCHEMBL3612846	0.86	BTK (0.40)	KDRBTKRIPK1FLT1TEK
	SCHEMBL276106	0.83	FLT3 (0.51)	KDRBTKRIPK1FLT1TEK
	SCHEMBL15222016	0.82	NEK7 (0.40)	KDRFLT1NTRK1PDGFRARET
	SCHEMBL3619756	0.82	FLT3 (0.41)	RIPK1FLT3
	SCHEMBL5279374	0.80	BTK (0.32)	BTKRIPK1FLT1TEK
	SCHEMBL276347	0.80	TEK (0.56)	KDRBTKRIPK1FLT1TEK
	SCHEMBL3619746	0.79	FLT1 (0.55)	KDRBTKRIPK1FLT1TEK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.