Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.40 |
| ▸ | CFD | P00746 | 12/20 | 0.35 |
| ▸ | CMA1 | P23946 | 2/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | CD38 | P28907 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3628889 | 0.93 | METTL3 (0.39) | METTL3CFDCMA1SLC22A12NOTUM | |
| SCHEMBL3627433 | 0.90 | METTL3 (0.40) | METTL3CFDCMA1SLC22A12NOTUM | |
| SCHEMBL3615826 | 0.89 | METTL3 (0.39) | METTL3CFDCMA1SLC22A12NOTUM | |
| SCHEMBL3615770 | 0.86 | METTL3 (0.38) | METTL3CFDCMA1NOTUMRORC | |
| SCHEMBL3625696 | 0.86 | METTL3 (0.44) | METTL3CFDCMA1NOTUM | |
| SCHEMBL3620072 | 0.85 | METTL3 (0.39) | METTL3CFDCMA1SLC22A12NOTUM | |
| SCHEMBL3627914 | 0.83 | METTL3 (0.46) | METTL3CFDCMA1SLC22A12NOTUM | |
| SCHEMBL3628451 | 0.83 | METTL3 (0.42) | METTL3CFDCMA1SLC22A12NOTUM | |
| SCHEMBL3623800 | 0.82 | METTL3 (0.41) | METTL3CFDCMA1SLC22A12NOTUM | |
| SCHEMBL3624158 | 0.82 | METTL3 (0.47) | METTL3CFDCMA1NOTUMRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060084665-A1 | Quinolizinone compound and use thereof as HIV integrase inhibitor | JAPAN TOBACCO INC. (JP) | 2006-04-20 | — | — | US | claimed |
| US-7745459-B2 | Quinolizinone compound and use thereof as HIV integrase inhibitor | JAPAN TOBACCO INC. (JP) | 2010-06-29 | — | — | US | disclosed |
| US-20060084665-A1 | Quinolizinone compound and use thereof as HIV integrase inhibitor | JAPAN TOBACCO INC. (JP) | 2006-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084665-A1 | Quinolizinone compound and use thereof as HIV integrase inhibitor | NQO2, ACE, CDK20 | METTL3 3971/4885CFD 4484/4885CMA1 738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.