Econazole

Econazole

SCHEMBL36213

Clc1ccc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1.O=[N+]([O-])O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ERG11

The experimentally established mechanism targets of Econazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 1.00
LMNA P02545 5/20 1.00
MEN1 O00255 4/20 1.00
KMT2A Q03164 4/20 1.00
TDP1 Q9NUW8 4/20 1.00
USP2 O75604 3/20 1.00
TP53 P04637 3/20 1.00
MAPT P10636 3/20 1.00
MAPK1 P28482 3/20 1.00
HTT P42858 3/20 1.00
HIF1A Q16665 3/20 1.00
NPSR1 Q6W5P4 3/20 1.00
HSP90AA1 P07900 3/20 1.00
TSHR P16473 2/20 1.00
NPY2R P49146 2/20 1.00
GAA P10253 2/20 1.00
RECQL P46063 2/20 1.00
NPY1R P25929 2/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
ALDH1A1 P00352 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Econazole SCHEMBL36214 1.00 CYP3A4 (1.00) CYP3A4LMNAMEN1KMT2ATDP1
Econazole SCHEMBL3692069 1.00 CYP3A4 (1.00) CYP3A4LMNAMEN1KMT2ATDP1
Econazole SCHEMBL29379555 1.00 CYP3A4 (1.00) CYP3A4LMNAMEN1KMT2ATDP1
Econazole SCHEMBL20456409 1.00 CYP3A4 (1.00) CYP3A4LMNAMEN1KMT2ATDP1
Miconazole SCHEMBL8200081 0.95 CYP3A4 (0.91) CYP3A4LMNAMEN1KMT2ATDP1
Nitric Acid SCHEMBL11488271 0.93 CYP3A4 (0.86) CYP3A4LMNAMEN1KMT2ATDP1
Econazole SCHEMBL7602990 0.92 IDO1 (1.00) CYP3A4LMNAMEN1KMT2ATDP1
Econazole SCHEMBL20482166 0.92 IDO1 (1.00) CYP3A4LMNAMEN1KMT2ATDP1
Econazole SCHEMBL34499 0.92 IDO1 (1.00) CYP3A4LMNAMEN1KMT2ATDP1
Econazole SCHEMBL7602993 0.92 IDO1 (1.00) CYP3A4LMNAMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4375 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025264604-A1 SKIN CARE COMPOSITION AND METHOD OF USING THE SAME THE PROCTER & GAMBLE COMPANY (US) 2025-12-26 WO claimed
US-20250381110-A1 SKIN CARE COMPOSITION AND METHOD OF USING THE SAME PROCTER & GAMBLE (US) 2025-12-18 US claimed
US-12303491-B2 Econazole nitrate medical patch and methods of use thereof TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2025-05-20 US claimed
US-20250127711-A1 COMPOSITION AND METHOD FOR TREATING FUNGAL SKIN CONDITIONS AND INFLAMMATION CMPD LICENSING, LLC (US) 2025-04-24 US claimed
US-12274830-B2 Nitric oxide inhalation therapy for infants with bronchiolitis BEYOND AIR LTD (IL) 2025-04-15 US claimed
WO-2025032112-A1 METHODS FOR THE TREATMENT OF TYPE 2-MEDIATED DISEASES Institut National de la Santé et de la Recherche Médicale (FR) 2025-02-13 WO claimed
CN-119013001-A Topical aerosol foam 阿尔库缇斯生物疗法股份有限公司 2024-11-22 CN claimed
EP-4456877-A1 TOPICAL AEROSOL FOAMS Arcutis Biotherapeutics, Inc. (US) 2024-11-06 EP claimed
US-12102712-B2 Composition and method for treating fungal skin conditions and inflammation CMPD LICENSING LLC (US) 2024-10-01 US claimed
US-20240282425-A1 AUTHENTICATION METHODS AND SYSTEMS FOR DISPENSED PRESCRIPTIONS LOW GORDON KEITH (US) 2024-08-22 US claimed
WO-1990011754-A1 AEROSOLIZED AZOLE ANTIFUNGALS FISONS PLC (GB) 1990-10-18 WO claimed
EP-0103995-B1 MEDICATED SUPPOSITORY CILAG AG (CH) 1990-04-11 EP claimed
US-4897269-A Administration of drugs with multiphase liposomal delivery system MEZEI ASSOCIATES LIMITED (CA) 1990-01-30 US claimed
CN-1031648-A Prevent mean that elastomeric material is made and manufacture method thereof HUTCHINSON (FR) 1989-03-15 CN claimed
US-4803066-A SYNERGISTIC MIXTURE OF AN IMIDAZOLE OR TRIAZOLE COMPOUND AND SILVER SULFADIAZINE SMITH & NEPHEW ASSOCIATED COMPANIES P.L.C. (GB) 1989-02-07 US claimed
US-4761288-A Multiphase liposomal drug delivery system MEZEI ASSOCIATES LIMITED (CA) 1988-08-02 US claimed
EP-0241175-A1 Topical antimicrobial pharmaceutical composition comprising a silver compound and an azole SMITH & NEPHEW plc (GB) 1987-10-14 EP claimed
US-4698359-A Medicated suppository CILAG, AG (CH) 1987-10-06 US claimed
EP-0125759-A2 Topical composition of antibiotics for application to the mucosa WARNER LAMBERT HOLLAND B.V. (NL) 1984-11-21 EP claimed
EP-0103995-A2 Medicated suppository CILAG AG (CH) 1984-03-28 EP claimed