Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 15/20 | 0.84 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4019777 | 1.00 | SIGMAR1 (0.84) | SIGMAR1MEN1KMT2ASLC2A1HTT | |
| SCHEMBL19505478 | 1.00 | SIGMAR1 (0.84) | SIGMAR1MEN1KMT2ASLC2A1HTT | |
| Hydrochloric Acid SCHEMBL28449997 | 0.98 | SIGMAR1 (0.82) | SIGMAR1MEN1KMT2ASLC2A1HTT | |
| Hydrochloric Acid SCHEMBL28835520 | 0.98 | SIGMAR1 (0.82) | SIGMAR1MEN1KMT2ASLC2A1HTT | |
| Hydrochloric Acid SCHEMBL4015078 | 0.98 | SIGMAR1 (0.82) | SIGMAR1MEN1KMT2ASLC2A1HTT | |
| SCHEMBL8091471 | 0.91 | SIGMAR1 (1.00) | SIGMAR1MEN1KMT2ASLC2A1 | |
| SCHEMBL22043276 | 0.91 | SIGMAR1 (1.00) | SIGMAR1MEN1KMT2ASLC2A1 | |
| SCHEMBL22043526 | 0.91 | SIGMAR1 (1.00) | SIGMAR1MEN1KMT2ASLC2A1 | |
| SCHEMBL21985949 | 0.91 | SIGMAR1 (1.00) | SIGMAR1MEN1KMT2ASLC2A1 | |
| SCHEMBL19469330 | 0.91 | SIGMAR1 (1.00) | SIGMAR1MEN1KMT2ASLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010128355-A2 | IMPROVED PROCESSES FOR PREPARING SUBSTANTIALLY PURE ARFORMOTEROL AND ITS INTERMEDIATES | ACTAVIS GROUP PTC EHF (IS) | 2010-11-11 | — | — | WO | disclosed |
| EP-1446380-A1 | FORMOTEROL TARTRATE PROCESS AND POLYMORPH | Sepracor Inc. (US) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003042165-A1 | FORMOTEROL TARTRATE PROCESS AND POLYMORPH | SEPRACOR INC. (US) | 2003-05-22 | — | — | WO | disclosed |
| EP-1093450-A1 | DESFORMOTEROL AND PROCESS FOR ITS PREPARATION | Sepracor Inc. (US) | 2001-04-25 | — | — | EP | disclosed |
| EP-1082293-A2 | FORMOTEROL POLYMORPHS | Sepracor Inc. (US) | 2001-03-14 | — | — | EP | disclosed |
| WO-2000021487-A2 | FORMOTEROL POLYMORPHS | SEPRACOR INC. (US) | 2000-04-20 | — | — | WO | disclosed |
| WO-1999067198-A1 | DESFORMOTEROL AND PROCESS FOR ITS PREPARATION | SEPRACOR INC. (US) | 1999-12-29 | — | — | WO | disclosed |
| EP-0390762-B1 | New bronchospasmolytic compounds and process for their preparation | DRACO AB (SE) | 1994-01-19 | — | — | EP | disclosed |
| EP-0390762-A1 | New bronchospasmolytic compounds and process for their preparation | Aktiebolaget Draco (SE) | 1990-10-03 | — | — | EP | disclosed |