Pentachlorophenol

Pentachlorophenol

SCHEMBL3621950

C=CC(=O)O.OCC(O)C(O)CO.Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.39
CYP2C9 P11712 4/20 0.39
TSHR P16473 3/20 0.39
HIF1A Q16665 3/20 0.39
HSD17B10 Q99714 3/20 0.37
LMNA P02545 2/20 0.37
HPGD P15428 2/20 0.37
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.32
MAPK1 P28482 1/20 0.32
PDE4A P27815 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sorbitol SCHEMBL7107557 0.93 PDE4A (0.41) CYP1A2CYP2C9TSHRHIF1AHSD17B10
Pentachlorophenol SCHEMBL17595165 0.84 TSHR (0.53) CYP1A2CYP2C9TSHRHIF1AHSD17B10
Pentachlorophenol SCHEMBL4417163 0.83 TSHR (0.35) CYP1A2CYP2C9TSHRHIF1AHSD17B10
E968 SCHEMBL29468146 0.82 LMNA (0.56) TSHRHSD17B10LMNAALDH1A1MAPK1
E968 SCHEMBL8127218 0.82 LMNA (0.56) TSHRHSD17B10LMNAALDH1A1MAPK1
E968 SCHEMBL3621953 0.82 LMNA (0.56) TSHRHSD17B10LMNAALDH1A1MAPK1
E968 SCHEMBL29429812 0.82 LMNA (0.56) TSHRHSD17B10LMNAALDH1A1MAPK1
E968 SCHEMBL3479791 0.82 LMNA (0.56) TSHRHSD17B10LMNAALDH1A1MAPK1
E968 SCHEMBL21625759 0.82 LMNA (0.56) TSHRHSD17B10LMNAALDH1A1MAPK1
E968 SCHEMBL31043056 0.82 LMNA (0.56) TSHRHSD17B10LMNAALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0466880-A1 POLYURETHANE-TYPE COMPOSITIONS CROSS-LINKABLE WITH IONIZING RADIATION FOR USE AS FINISHING COATINGS ON METAL OR METALLIZED SURFACES SOCIETE CELLIOSE LOBO ENTREPRISE (FR) 1992-01-22 EP claimed
WO-1991011479-A1 POLYURETHANE-TYPE COMPOSITIONS CROSS-LINKABLE WITH IONIZING RADIATION FOR USE AS FINISHING COATINGS ON METAL OR METALLIZED SURFACES SOCIETE CELLIOSE LOBO ENTREPRISE (FR) 1991-08-08 WO claimed
EP-2535774-B1 Image bearing drum, image forming apparatus, image forming method, and process cartridge RICOH CO LTD (JP) 2014-07-30 EP disclosed
EP-2125941-B1 A LAYERED STRUCTURE COMPRISING NANOPARTICLES SAINT GOBAIN PERFORMANCE PLAST (BE) 2013-05-01 EP disclosed
US-20120321348-A1 IMAGE BEARING DRUM, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2012-12-20 US disclosed
EP-2535774-A1 Image bearing drum, image forming apparatus, image forming method, and process cartridge Ricoh Company, Ltd. (JP) 2012-12-19 EP disclosed
US-20100231836-A1 PHASE DIFFERENCE CONTROL MEMBER, LIQUID CRYSTAL DISPLAY AND LIQUID CRYSTAL MATERIAL COMPOSITION FOR FORMING PHASE DIFFERENCE LAYER DAI NIPPON PRINTING CO., LTD. (JP) 2010-09-16 US disclosed
US-20090305013-A1 LAYERED STRUCTURE COMPRISING NANOPARTICLES NV BERKAERT SA 2009-12-10 US disclosed
EP-2125941-A1 A LAYERED STRUCTURE COMPRISING NANOPARTICLES NV Bekaert SA (BE) 2009-12-02 EP disclosed
WO-2008104502-A1 A LAYERED STRUCTURE COMPRISING NANOPARTICLES NV BEKAERT SA (BE) 2008-09-04 WO disclosed
US-5929954-A Liquid crystal display device and liquid crystal projection display device having a light directivity controller of light beams MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1999-07-27 US disclosed
US-5760849-A Liquid crystal display device and liquid crystal projection display device including means for controlling direction of light beams MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1998-06-02 US disclosed
EP-0368165-A2 Curable resin compositions IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1990-05-16 EP disclosed
EP-0257812-A2 Nitrile acrylate coating composition containing pendant functionality and a radiation curable process THE STANDARD OIL COMPANY (US) 1988-03-02 EP disclosed