SCHEMBL3621986

SCHEMBL3621986

CSc1ccc(OP(O)(O)=S)cc1C

nearest known ligand 0.69

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.69
CYP3A4 P08684 2/20 0.69
TSHR P16473 2/20 0.69
HSD17B10 Q99714 1/20 0.69
HPGD P15428 1/20 0.48
SLC6A4 P31645 6/20 0.38
TAS1R3 Q7RTX0 3/20 0.35
TAS1R1 Q7RTX1 3/20 0.35
THRB P10828 1/20 0.34
SLC6A2 P23975 3/20 0.31
SLC6A3 Q01959 3/20 0.31
HRH3 Q9Y5N1 3/20 0.31
NPSR1 Q6W5P4 1/20 0.30
INPPL1 O15357 1/20 0.30
INPP5A Q14642 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10109462 0.83 ALDH1A1 (0.65) ALDH1A1CYP3A4TSHRHSD17B10HPGD
SCHEMBL27321129 0.82 ALDH1A1 (0.56) ALDH1A1CYP3A4TSHRHSD17B10HPGD
Fenthion SCHEMBL28673475 0.82 ALDH1A1 (0.94) ALDH1A1CYP3A4TSHRHSD17B10HPGD
Fenthion SCHEMBL29441335 0.81 ALDH1A1 (1.00) ALDH1A1CYP3A4TSHRHSD17B10HPGD
Fenthion SCHEMBL6739014 0.81 ALDH1A1 (1.00) ALDH1A1CYP3A4TSHRHSD17B10HPGD
Fenthion SCHEMBL26907 0.81 ALDH1A1 (1.00) ALDH1A1CYP3A4TSHRHSD17B10HPGD
SCHEMBL3621984 0.80 CYP3A4 (0.60) ALDH1A1CYP3A4TSHRHSD17B10HPGD
SCHEMBL11775338 0.79 ALDH1A1 (0.56) ALDH1A1CYP3A4TSHRHSD17B10HPGD
SCHEMBL8586119 0.79 ALDH1A1 (0.55) ALDH1A1CYP3A4TSHRHSD17B10HPGD
SCHEMBL120468 0.78 ALDH1A1 (0.70) ALDH1A1CYP3A4TSHRHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4605431-A ANTIDOTES FOR THIOLCARBAMATE HERBICIDES; PLANT SAFENING AGENTS MONSANTO COMPANY (US) 1986-08-12 US claimed
EP-0017738-B1 AN INSECTICIDAL AND MITICIDAL COMPOSITION WHICH CONTAINS A CARBAMATE AND AN ORGANIC PHOSPHORUS COMPOUND, AND A METHOD OF CONTROLLING INSECTS AND MITES THEREWITH IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-08-08 EP claimed
US-4379716-A Compositions and methods for reducing herbicidal injury MONSANTO COMPANY (US) 1983-04-12 US claimed
CN-109042635-B Fenthion aqueous emulsion and preparation method and application thereof 柳州市万友家庭卫生害虫防治所 2021-04-20 CN disclosed
CN-109042635-A Entex aqueous emulsion and the preparation method and application thereof 柳州市万友家庭卫生害虫防治所 2018-12-21 CN disclosed
EP-2143331-B1 Fan type chemicals diffusing apparatus FUMAKILLA LTD (JP) 2018-06-20 EP disclosed
CN-105532718-A Ultralow-volume spraying agent containing fenthion and application thereof JINAN SHUNHAO BIOTECHNOLOGY CO LTD 2016-05-04 CN disclosed
CN-101153841-B Method for detecting content of fenthion UNIV MYONGJI 2011-07-13 CN disclosed
US-20100168030-A1 Methods and compositions for treatment of organophosphate-caused pathology ARMY, UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE 2010-07-01 US disclosed
EP-2143331-A2 Fan type chemicals diffusing apparatus Fumakilla Limited (JP) 2010-01-13 EP disclosed
CN-101153841-A Method for detecting content of fenthion UNIV MYONGJI (KR) 2008-04-02 CN disclosed
US-5365691-A Methods and agents for combating cockroaches BAYER AKTIENGESELLSCHAFT (DE) 1994-11-22 US disclosed
US-5326573-A Carrier particles for plant pesticides and herbicides, adhesives BAYER AKTIENGESELLSCHAFT (DE) 1994-07-05 US disclosed
EP-0332387-B1 Triazole derivatives, their preparation and their use as fungicides SANKYO CO (JP) 1993-11-24 EP disclosed
EP-0537957-A1 Fungicidal silicon-containing compounds, their preparation and their agrochemical and medicinal uses Sankyo Company Limited (JP) 1993-04-21 EP disclosed
US-5178872-A PESTICIDAL COMPOSITION CONTAINING A MICROENCAPSULATED ORGANO-PHOSPHORUS OR CARBAMATE IN A PYRETHROID DISPERSION SUMITOMO CHEMICAL CO., LTD. (JP) 1993-01-12 US disclosed
EP-0427991-A1 Improved pesticidal composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-05-22 EP disclosed
US-4443438-A Insecticidal and/or acaricidal composition exhibiting low toxicity to mammals and fish SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-04-17 US disclosed
US-4357348-A Insecticidal and/or acaricidal composition exhibiting low toxicity to mammals and fish SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-11-02 US disclosed
US-4062946-A 3-ISOTHIAZOLONES ROHM AND HAAS COMPANY (US) 1977-12-13 US disclosed