Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 5/20 | 0.36 |
| ▸ | NOS1 | P29475 | 3/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3559463 | 0.84 | NOS2 (0.48) | NOS2NOS1 | |
| SCHEMBL13037318 | 0.76 | NOS2 (0.48) | NOS2NOS1 | |
| SCHEMBL3566344 | 0.71 | NOS2 (0.63) | NOS2NOS1 | |
| SCHEMBL14529945 | 0.68 | NOS2 (0.48) | NOS2NOS1 | |
| SCHEMBL3562977 | 0.68 | NOS2 (0.46) | NOS2NOS1 | |
| SCHEMBL3563089 | 0.65 | GAA (0.42) | NOS2NOS1 | |
| SCHEMBL3569037 | 0.63 | NOS2 (0.65) | NOS2NOS1 | |
| SCHEMBL3567031 | 0.63 | NOS2 (0.76) | NOS2NOS1 | |
| SCHEMBL3559011 | 0.63 | NOS2 (0.60) | NOS2NOS1 | |
| SCHEMBL13037142 | 0.62 | NOS2 (0.57) | NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100094021-A1 | NOVEL METHOD OF PREPARATION OF 5-CHLORO-3-IMIDAZOL-1-YL-[1,2,4]THIADIAZOLE AND (3-IMIDAZOL-1-YL-[1,2,4]THIADIAZOL-5YL)-DIALKYL-AMINES | KALYPSYS, INC. (US) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100094021-A1 | NOVEL METHOD OF PREPARATION OF 5-CHLORO-3-IMIDAZOL-1-YL-[1,2,4]THIADIAZOLE AND (3-IMIDAZOL-1-YL-[1,2,4]THIADIAZOL-5YL)-DIALKYL-AMINES | DCLK2, TH, DCLK3 | NOS2 983/4885NOS1 777/4885CPB2 4722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.