Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1476986 | 0.98 | TSHR (0.65) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| Hydrochloric Acid SCHEMBL5385813 | 0.97 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| Bromide SCHEMBL29140481 | 0.94 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| Bromide SCHEMBL28633922 | 0.94 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| Bromide SCHEMBL29140485 | 0.94 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| Bromide SCHEMBL1867369 | 0.94 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| Bromide SCHEMBL8196037 | 0.94 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| Bromide SCHEMBL3630565 | 0.94 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| Bromide SCHEMBL28635420 | 0.94 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| Bromide SCHEMBL29140476 | 0.94 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106188557-B | The method of unsaturated halogenated hydrocarbons copolymerized grafting cationic side chain preparation highly resistance chamotte mould polycarboxylate dispersant | 北京工业大学 | 2019-04-05 | — | — | CN | claimed |
| CN-106188556-B | Poly carboxylic acid modified carboxylic acid halides is grafted the method that compound side chain prepares cement water reducing agent | 北京工业大学 | 2019-04-05 | — | — | CN | claimed |
| CN-106084243-B | The method that backbone modification isocyanates grafted cation side chain prepares polycarboxylate water-reducer | 北京工业大学 | 2019-03-22 | — | — | CN | claimed |
| CN-106117564-B | A kind of preparation method of the highly resistance chamotte mould cement dispersants of graft esterification cationic side chain | 北京工业大学 | 2019-03-22 | — | — | CN | claimed |
| CN-106188558-B | The method for preparing cement water reducing agent as monomer using p styrene sulfonic acid salt | 北京工业大学 | 2018-12-25 | — | — | CN | claimed |
| CN-106117468-B | The preparation method of the high anti-chamotte mould cement water reducing agent of graft copolymerization cationic side chain | 北京工业大学 | 2018-03-30 | — | — | CN | claimed |
| CN-106117461-B | The method that alkenyl alcoholysis of acyl chloride prepares polymeric monomer synthesis polycarboxylate water-reducer | 北京工业大学 | 2018-03-30 | — | — | CN | claimed |
| CN-106117450-B | Method based on Hoffmann rearrangement reaction synthesizing cationic type polycarboxylate water-reducer | 北京工业大学 | 2018-03-16 | — | — | CN | claimed |
| CN-106188428-B | The method that the copolyreaction of benzene sulfonic acid esters surface-active macromonomer synthesizes high performance water reducing agent of polyocarboxy acid | 北京工业大学 | 2018-03-16 | — | — | CN | claimed |
| CN-106350049-A | Method for improving polymer flooding effect, and polymer flooding composition and application thereof | 中国海洋石油总公司 | 2017-01-25 | — | — | CN | claimed |
| CN-106188428-A | The method of benzenesulfonic acid esters surface-active macromonomer copolyreaction synthesis high performance water reducing agent of polyocarboxy acid | 北京工业大学 | 2016-12-07 | — | — | CN | claimed |
| CN-106188556-A | The method that cement water reducing agent prepared by the compound side chain of poly carboxylic acid modified carboxylic acid halides grafting | 北京工业大学 | 2016-12-07 | — | — | CN | claimed |
| CN-106188557-A | The method that unsaturated halogenated hydrocarbons copolymerized grafting cationic side chain prepares high anti-chamotte mould polycarboxylate dispersant | 北京工业大学 | 2016-12-07 | — | — | CN | claimed |
| CN-106188558-A | The method preparing cement water reducing agent for monomer with p styrene sulfonic acid salt | 北京工业大学 | 2016-12-07 | — | — | CN | claimed |
| CN-106117564-A | A kind of preparation method of the height anti-chamotte mould cement dispersants of graft esterification cationic side chain | 北京工业大学 | 2016-11-16 | — | — | CN | claimed |
| CN-106117468-A | The preparation method of the height anti-chamotte mould cement water reducing agent of graft copolymerization cationic side chain | 北京工业大学 | 2016-11-16 | — | — | CN | claimed |
| CN-106117461-A | Thiazolinyl alcoholysis of acyl chloride prepares the method for polymeric monomer synthesis polycarboxylate water-reducer | 北京工业大学 | 2016-11-16 | — | — | CN | claimed |
| CN-106117450-A | Method based on Hoffmann rearrangement reaction synthesizing cationic type polycarboxylate water-reducer | 北京工业大学 | 2016-11-16 | — | — | CN | claimed |
| CN-106084243-A | The method that polycarboxylate water-reducer prepared by backbone modification isocyanates grafted cation side chain | 北京工业大学 | 2016-11-09 | — | — | CN | claimed |
| US-20250135745-A1 | ANTISTATIC FABRIC ARTICLE | 3M INNOVATIVE PROPERTIES COMPANY | 2025-05-01 | — | — | US | disclosed |
| EP-4384387-A1 | ANTISTATIC FABRIC ARTICLE | 3M Innovative Properties Company (US) | 2024-06-19 | — | — | EP | disclosed |
| WO-2023017392-A1 | ANTISTATIC FABRIC ARTICLE | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-02-16 | — | — | WO | disclosed |
| CN-107964071-B | Water-dispersible polymers and their use | 清华大学 | 2020-02-21 | — | — | CN | disclosed |
| CN-107964070-B | Water-soluble polymer and application thereof | 清华大学 | 2020-02-18 | — | — | CN | disclosed |
| CN-106188557-B | The method of unsaturated halogenated hydrocarbons copolymerized grafting cationic side chain preparation highly resistance chamotte mould polycarboxylate dispersant | 北京工业大学 | 2019-04-05 | — | — | CN | disclosed |
| CN-106188556-B | Poly carboxylic acid modified carboxylic acid halides is grafted the method that compound side chain prepares cement water reducing agent | 北京工业大学 | 2019-04-05 | — | — | CN | disclosed |
| CN-106117564-B | A kind of preparation method of the highly resistance chamotte mould cement dispersants of graft esterification cationic side chain | 北京工业大学 | 2019-03-22 | — | — | CN | disclosed |
| CN-106084243-B | The method that backbone modification isocyanates grafted cation side chain prepares polycarboxylate water-reducer | 北京工业大学 | 2019-03-22 | — | — | CN | disclosed |
| CN-106188558-B | The method for preparing cement water reducing agent as monomer using p styrene sulfonic acid salt | 北京工业大学 | 2018-12-25 | — | — | CN | disclosed |
| CN-106117461-B | The method that alkenyl alcoholysis of acyl chloride prepares polymeric monomer synthesis polycarboxylate water-reducer | 北京工业大学 | 2018-03-30 | — | — | CN | disclosed |
| CN-106117468-B | The preparation method of the high anti-chamotte mould cement water reducing agent of graft copolymerization cationic side chain | 北京工业大学 | 2018-03-30 | — | — | CN | disclosed |
| CN-106117450-B | Method based on Hoffmann rearrangement reaction synthesizing cationic type polycarboxylate water-reducer | 北京工业大学 | 2018-03-16 | — | — | CN | disclosed |
| CN-106188428-B | The method that the copolyreaction of benzene sulfonic acid esters surface-active macromonomer synthesizes high performance water reducing agent of polyocarboxy acid | 北京工业大学 | 2018-03-16 | — | — | CN | disclosed |
| CN-106188428-A | The method of benzenesulfonic acid esters surface-active macromonomer copolyreaction synthesis high performance water reducing agent of polyocarboxy acid | 北京工业大学 | 2016-12-07 | — | — | CN | disclosed |
| CN-106188557-A | The method that unsaturated halogenated hydrocarbons copolymerized grafting cationic side chain prepares high anti-chamotte mould polycarboxylate dispersant | 北京工业大学 | 2016-12-07 | — | — | CN | disclosed |
| CN-106188558-A | The method preparing cement water reducing agent for monomer with p styrene sulfonic acid salt | 北京工业大学 | 2016-12-07 | — | — | CN | disclosed |
| CN-106188556-A | The method that cement water reducing agent prepared by the compound side chain of poly carboxylic acid modified carboxylic acid halides grafting | 北京工业大学 | 2016-12-07 | — | — | CN | disclosed |
| CN-106117468-A | The preparation method of the height anti-chamotte mould cement water reducing agent of graft copolymerization cationic side chain | 北京工业大学 | 2016-11-16 | — | — | CN | disclosed |
| CN-106117564-A | A kind of preparation method of the height anti-chamotte mould cement dispersants of graft esterification cationic side chain | 北京工业大学 | 2016-11-16 | — | — | CN | disclosed |
| CN-106117450-A | Method based on Hoffmann rearrangement reaction synthesizing cationic type polycarboxylate water-reducer | 北京工业大学 | 2016-11-16 | — | — | CN | disclosed |
| CN-106117461-A | Thiazolinyl alcoholysis of acyl chloride prepares the method for polymeric monomer synthesis polycarboxylate water-reducer | 北京工业大学 | 2016-11-16 | — | — | CN | disclosed |
| CN-106084243-A | The method that polycarboxylate water-reducer prepared by backbone modification isocyanates grafted cation side chain | 北京工业大学 | 2016-11-09 | — | — | CN | disclosed |
| US-9260612-B2 | Antistatic article, method of making the same, and display device having the same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-02-16 | — | — | US | disclosed |
| EP-2178998-B1 | ANTISTATIC ARTICLE, METHOD OF MAKING THE SAME, AND DISPLAY DEVICE HAVING THE SAME | 3M INNOVATIVE PROPERTIES CO (US) | 2014-03-05 | — | — | EP | disclosed |
| US-20130236702-A1 | ANTISTATIC ARTICLE, METHOD OF MAKING THE SAME, AND DISPLAY DEVICE HAVING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-09-12 | — | — | US | disclosed |
| US-8449970-B2 | Antistatic article, method of making the same, and display device having the same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-05-28 | — | — | US | disclosed |
| EP-2178998-A2 | ANTISTATIC ARTICLE, METHOD OF MAKING THE SAME, AND DISPLAY DEVICE HAVING THE SAME | 3M Innovative Properties Company (US) | 2010-04-28 | — | — | EP | disclosed |
| US-20090029129-A1 | ANTISTATIC ARTICLE, METHOD OF MAKING THE SAME, AND DISPLAY DEVICE HAVING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY | 2009-01-29 | — | — | US | disclosed |
| US-20090029129-A1 | ANTISTATIC ARTICLE, METHOD OF MAKING THE SAME, AND DISPLAY DEVICE HAVING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY | 2009-01-29 | — | — | US | disclosed |
| WO-2009014897-A2 | ANTISTATIC ARTICLE, METHOD OF MAKING THE SAME, AND DISPLAY DEVICE HAVING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-01-29 | — | — | WO | disclosed |