Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1906165 | 0.87 | LTA4H (0.55) | LTA4HKCNH2 | |
| SCHEMBL12223106 | 0.87 | LTA4H (0.55) | LTA4HKCNH2 | |
| SCHEMBL1906942 | 0.84 | LTA4H (0.66) | LTA4HKCNH2 | |
| SCHEMBL12222885 | 0.84 | LTA4H (0.66) | LTA4HKCNH2 | |
| SCHEMBL1904690 | 0.83 | LTA4H (0.48) | LTA4HKCNH2 | |
| SCHEMBL12223117 | 0.83 | LTA4H (0.48) | LTA4HKCNH2 | |
| SCHEMBL3621856 | 0.80 | LTA4H (0.47) | LTA4HKCNH2 | |
| SCHEMBL1902111 | 0.77 | LTA4H (0.55) | LTA4HKCNH2 | |
| SCHEMBL12265719 | 0.77 | LTA4H (0.55) | LTA4HKCNH2 | |
| SCHEMBL12223114 | 0.77 | LTA4H (0.55) | LTA4HKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217237-A1 | ARYL-SUBSTITUTED BRIDGED OR FUSED DIAMINES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE | Janssen Pharmaceutica N.V. (BE) | 2010-08-18 | — | — | EP | claimed |
| WO-2009058347-A1 | ARYL-SUBSTITUTED BRIDGED OR FUSED DIAMINES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-05-07 | — | — | WO | claimed |