SCHEMBL3624152

SCHEMBL3624152

NC(c1ccc(Cl)cc1)(c1ccc2c(c1)c(-c1cccc(Cl)c1)cc1nnnn12)c1cncn1CI

nearest known ligand 0.78

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FNTA P49354 17/20 0.78
FNTB P49356 17/20 0.78
PGGT1B P53609 4/20 0.78
CYP3A4 P08684 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1683527 0.88 FNTA (1.00) FNTAFNTBPGGT1BCYP3A4
SCHEMBL1683562 0.81 FNTA (0.88) FNTAFNTBPGGT1BCYP3A4
SCHEMBL7097457 0.81 FNTA (0.85) FNTAFNTBPGGT1BCYP3A4
SCHEMBL5016841 0.80 FNTA (0.85) FNTAFNTBPGGT1BCYP3A4
SCHEMBL5023173 0.79 FNTA (0.82) FNTAFNTBPGGT1BCYP3A4
SCHEMBL5022769 0.78 FNTA (0.81) FNTAFNTBPGGT1BCYP3A4
SCHEMBL6303247 0.78 FNTA (0.79) FNTAFNTBPGGT1B
SCHEMBL5016840 0.76 FNTA (0.78) FNTAFNTBPGGT1BCYP3A4
SCHEMBL7094572 0.75 FNTA (0.65) FNTAFNTBPGGT1BCYP3A4
SCHEMBL5022669 0.75 FNTA (0.75) FNTAFNTBPGGT1BCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2155197-A2 TREATMENT OF LYSOSOMAL STORAGE DISEASES Link Medicine Corporation (US) 2010-02-24 EP claimed
WO-2008112525-A2 TREATMENT OF LYSOSOMAL STORAGE DISEASES LINK MEDICINE CORPORATION (US) 2008-09-18 WO claimed