Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 17/20 | 0.65 |
| ▸ | FNTB | P49356 | 17/20 | 0.65 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1683527 | 0.79 | FNTA (1.00) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL3624152 | 0.75 | FNTA (0.78) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL7097457 | 0.75 | FNTA (0.85) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL1683562 | 0.74 | FNTA (0.88) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL5016841 | 0.73 | FNTA (0.85) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL14588606 | 0.71 | FNTA (0.71) | FNTAFNTBPGGT1B | |
| SCHEMBL5022769 | 0.71 | FNTA (0.81) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL6303247 | 0.71 | FNTA (0.79) | FNTAFNTBPGGT1B | |
| SCHEMBL5023173 | 0.70 | FNTA (0.82) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL5657267 | 0.70 | FNTA (0.54) | FNTAFNTBPGGT1BHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140935-B1 | 1,2-ANNELATED QUINOLINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2003-05-14 | — | — | EP | claimed |