SCHEMBL3624271

SCHEMBL3624271

CCCCCc1ccc(OC(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 7/20 0.58
MAPT P10636 3/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
THRA P10827 6/20 0.56
RARB P10826 5/20 0.51
NPC1 O15118 2/20 0.51
LMNA P02545 2/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
KMT2A Q03164 3/20 0.50
MEN1 O00255 2/20 0.50
NFKB1 P19838 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
PRSS1 P07477 1/20 0.50
ACR P10323 1/20 0.50
ALDH1A1 P00352 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9842392 1.00 THRB (0.58) THRBMAPTSMN1; SMN2THRARARB
SCHEMBL18434843 0.99 THRB (0.58) THRBMAPTSMN1; SMN2THRARARB
SCHEMBL16073026 0.99 THRB (0.58) THRBMAPTSMN1; SMN2THRARARB
SCHEMBL12125123 0.99 THRB (0.58) THRBMAPTSMN1; SMN2THRARARB
SCHEMBL11964524 0.99 THRB (0.58) THRBMAPTSMN1; SMN2THRARARB
SCHEMBL15373862 0.99 THRB (0.58) THRBMAPTSMN1; SMN2THRARARB
SCHEMBL13783616 0.99 THRB (0.58) THRBMAPTSMN1; SMN2THRARARB
SCHEMBL11547550 0.96 MAPT (0.61) THRBMAPTSMN1; SMN2THRARARB
SCHEMBL11548353 0.96 MAPT (0.61) THRBMAPTSMN1; SMN2THRARARB
SCHEMBL11548728 0.96 MAPT (0.61) THRBMAPTSMN1; SMN2THRARARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE37270-E1 EXCELLENT ELECTRO-OPTIC STEEPNESS AND VIEWING ANGLE COMBINED WITH BIREFRINGENCE FOR USE IN STANDARD DISPLAY CELLS; MIXTURE OF 4-CYANO-3-FLUOROPHENYL BENZOATES, BENZONITRILES, ALKYLPHENYL ESTERS OF CYCLOHEXANE OR PHENYLCARBOXYLIC ACIDS MERCK PATENT GESELLSCHAFT (DE) 2001-07-10 US claimed
EP-0285617-B1 LIQUID CRYSTAL PHASE MERCK PATENT GmbH (DE) 1991-12-27 EP claimed
US-4886621-A ACCEPTABLE COMBINATION OF THRESHOLD STEEPNESS, VIEWING ANGLE AND TEMPERATURE DEPENDENCE AT LOW THRESHOLD VOLTAGE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-12-12 US claimed
US-11497687-B2 Chromic compositions TheUnseen Limited (GB) 2022-11-15 US disclosed
US-20200206096-A1 Chromic Compositions TheUnseen Limited (GB) 2020-07-02 US disclosed
EP-3641893-A1 CHROMIC COMPOSITIONS Theunseen Limited (GB) 2020-04-29 EP disclosed
CN-110997070-A Color-changing composition 泽安西恩有限公司 2020-04-10 CN disclosed
US-20190203138-A1 PHASE CHANGE MATERIALS FOR ENHANCED HEAT TRANSFER FLUID PERFORMANCE EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2019-07-04 US disclosed
US-20190203151-A1 FLAT VISCOSITY FLUIDS AND LUBRICATING OILS BASED ON LIQUID CRYSTAL BASE STOCKS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2019-07-04 US disclosed
WO-2018234530-A1 CHROMIC COMPOSITIONS THEUNSEEN (GB) 2018-12-27 WO disclosed
US-9507185-B2 Switch element comprising a liquid crystalline medium MERCK PATENT GMBH (DE) 2016-11-29 US disclosed
EP-0394906-B1 Liquid crystalline composition MERCK PATENT GMBH (DE) 1995-12-20 EP disclosed
EP-0285617-B1 LIQUID CRYSTAL PHASE MERCK PATENT GmbH (DE) 1991-12-27 EP disclosed
EP-0394906-A2 Liquid crystalline composition MERCK PATENT GmbH (DE) 1990-10-31 EP disclosed
US-4886621-A ACCEPTABLE COMBINATION OF THRESHOLD STEEPNESS, VIEWING ANGLE AND TEMPERATURE DEPENDENCE AT LOW THRESHOLD VOLTAGE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-12-12 US disclosed
US-4853149-A STABILITY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-08-01 US disclosed
EP-0285617-A1 LIQUID CRYSTAL PHASE. MERCK PATENT GMBH (DE) 1988-10-12 EP disclosed
US-4737312-A Liquid crystal composition MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1988-04-12 US disclosed
WO-1988002018-A1 LIQUID CRYSTAL PHASE MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1988-03-24 WO disclosed
WO-1986002375-A1 LIQUID CRYSTAL COMPOSITION MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1986-04-24 WO disclosed