Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1955193 | 0.88 | CA12 (0.50) | NFE2L2TSHRSMN1; SMN2KDM4ELMNA | |
| Acetamide SCHEMBL9643066 | 0.86 | NFE2L2 (0.53) | NFE2L2TSHRSMN1; SMN2KDM4ELMNA | |
| SCHEMBL28945296 | 0.85 | CA1 (0.47) | NFE2L2TSHRSMN1; SMN2KDM4ELMNA | |
| SCHEMBL13400205 | 0.84 | NFE2L2 (0.43) | NFE2L2SMN1; SMN2KDM4ELMNAHPGD | |
| SCHEMBL2160010 | 0.84 | NFE2L2 (0.56) | NFE2L2TSHRSMN1; SMN2KDM4ELMNA | |
| SCHEMBL3952526 | 0.84 | CA1 (0.59) | TSHRSMN1; SMN2KDM4ELMNACA12 | |
| SCHEMBL3327023 | 0.82 | MAPK1 (0.58) | NFE2L2TSHRSMN1; SMN2KDM4ELMNA | |
| SCHEMBL2160012 | 0.82 | NFE2L2 (0.54) | NFE2L2TSHRSMN1; SMN2KDM4ELMNA | |
| SCHEMBL6963260 | 0.82 | NFE2L2 (0.54) | NFE2L2TSHRSMN1; SMN2KDM4ELMNA | |
| SCHEMBL28953567 | 0.82 | CA12 (0.48) | TSHRSMN1; SMN2KDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024980-A1 | 4'-AMINO CYCLIC COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-03-04 | — | — | WO | disclosed |