SCHEMBL3624741

SCHEMBL3624741

CCCCc1ccc(OB(Oc2ccc(CCCC)c(CCCC)c2CCCC)Oc2ccc(CCCC)c(CCCC)c2CCCC)c(CCCC)c1CCCC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.37
NCEH1 Q6PIU2 1/20 0.35
CTRC Q99895 1/20 0.34
ALOX5 P09917 2/20 0.33
PTGS2 P35354 1/20 0.33
LIPG Q9Y5X9 1/20 0.33
HTT P42858 3/20 0.32
TSHR P16473 2/20 0.32
MEN1 O00255 2/20 0.32
MAPT P10636 2/20 0.32
KMT2A Q03164 2/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
ALOX15 P16050 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MAPK1 P28482 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
NPC1 O15118 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3617260 0.93 TYR (0.42) TYRALOX5PTGS2LIPGHTT
SCHEMBL3624743 0.86 TYR (0.39) TYRNCEH1CTRCALOX5PTGS2
SCHEMBL3627072 0.85 KDM4E (0.32) NCEH1ALOX5HPGD
SCHEMBL28916682 0.85 TYR (0.41) TYRNCEH1CTRCALOX5PTGS2
SCHEMBL10419164 0.85 TYR (0.34) TYRNCEH1CTRCALOX5PTGS2
SCHEMBL29278307 0.81 LIPG (0.44) TYRALOX5PTGS2LIPGHTT
SCHEMBL4633219 0.80 TYR (0.50) TYRCTRCALOX5LIPGHTT
SCHEMBL30044969 0.80 TYR (0.50) TYRCTRCALOX5LIPGHTT
SCHEMBL3617262 0.80 LIPG (0.46) TYRALOX5PTGS2LIPGHTT
SCHEMBL705053 0.80 TYR (0.38) TYRNCEH1CTRCALOX5PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7648947-B2 Lubricating oil composition for internal combustion engine NIPPON OIL CORPORATION (JP) 2010-01-19 US disclosed
US-20080020952-A1 Lubricant Composition NIPPON OIL CORPORATION (JP) 2008-01-24 US disclosed
EP-1835013-A1 LUBRICATING OIL COMPOSITION Nippon Oil Corporation (JP) 2007-09-19 EP disclosed
US-20050245402-A1 Lubricating oil composition for internal combustion engine NIPPON OIL CORPORATION (JP) 2005-11-03 US disclosed
EP-1535985-A1 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE Nippon Oil Corporation (JP) 2005-06-01 EP disclosed