Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.65 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3624849 | 1.00 | DNM1 (0.65) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3617767 | 1.00 | DNM1 (0.65) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3619955 | 1.00 | DNM1 (0.65) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3620472 | 1.00 | DNM1 (0.65) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL20017999 | 1.00 | DNM1 (0.65) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL24107253 | 1.00 | DNM1 (0.65) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3622910 | 1.00 | DNM1 (0.65) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL1164952 | 1.00 | DNM1 (0.65) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL1688008 | 1.00 | DNM1 (0.65) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL12249976 | 1.00 | DNM1 (0.65) | DNM1MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191490-B1 | PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF | MEDIMMUNE LTD (GB) | 2019-08-07 | — | — | EP | disclosed |
| US-7789934-B2 | Combination of an N-alkyl- or N,N-dialkylpolyhydroxyalkanamide and a metal soap, an alkylenebisfatty amide, or an N-alkylalkanamide; improves both flowability and lubricity, regardless of a presence or absence of a complicated pretreatment step. | KABUSHIKI KAISHA KOBE SEIKO SHO (JP) | 2010-09-07 | — | — | US | disclosed |
| US-20070154340-A1 | Lubricant for powder metallurgy, powdery mixture for powder metallurgy, and process for producing sinter | KABUSHIKI KAISHA KOBE SEIKO SHO (JP) | 2007-07-05 | — | — | US | disclosed |