⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27402978 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL11933924 | 0.78 | — | — | |
| SCHEMBL20307389 | 0.76 | — | — | |
| SCHEMBL3624950 | 0.76 | — | — | |
| SCHEMBL4240044 | 0.76 | — | — | |
| SCHEMBL20569423 | 0.76 | — | — | |
| SCHEMBL30462443 | 0.74 | ALDH1A1 (0.35) | — | |
| SCHEMBL16027996 | 0.74 | ALDH1A1 (0.30) | — | |
| SCHEMBL11829301 | 0.74 | GAA (0.39) | — | |
| SCHEMBL18857103 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133271-A1 | BICYCLIC PHTHALAZIN-1(2H)-ONE DERIVATIVES AND RELATED USES | NodThera Limited (GB) | 2023-07-13 | — | — | WO | disclosed |
| CN-110248941-B | Aryl-or heteroaryl-substituted imidazopyridine derivatives and their use as pesticides | 拜耳公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-114423748-A | Novel heteroaryl triazole compounds as pesticides | 拜耳公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-114071997-A | High spreading ULV formulations for agrochemical Compound II | 拜耳公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-114025608-A | ULV formulations with high spreading and absorption | 拜耳公司 | 2022-02-08 | — | — | CN | disclosed |
| CN-114007421-A | Absorption-promoting ULV formulations | 拜耳公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-113994970-A | Substituted sulfonamides for combating animal pests | 拜耳公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-113939509-A | Novel heteroaryl substituted aminoalkylazole compounds as pesticides | 拜耳动物保健有限责任公司 | 2022-01-14 | — | — | CN | disclosed |
| CN-113710669-A | Fused bicyclic heterocyclic derivatives as pesticides | 拜耳公司 | 2021-11-26 | — | — | CN | disclosed |
| US-20210340105-A1 | AMINOPYRIDINE COMPOUNDS AND METHODS FOR THE PREPARATION AND USE THEREOF | Cortexyme, Inc. (US) | 2021-11-04 | — | — | US | disclosed |
| EP-3468966-A1 | INHIBITORS OF THE MENIN-MLL INTERACTION | Vitae Pharmaceuticals, Inc. (US) | 2019-04-17 | — | — | EP | disclosed |
| EP-3328840-A1 | SUBSTITUTED TRIAZOLO BICYCLIC COMPOUNDS AS PDE2 INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2018-06-06 | — | — | EP | disclosed |
| WO-2017214367-A1 | INHIBITORS OF THE MENIN-MLL INTERACTION | VITAE PHARMACEUTICALS, INC. (US) | 2017-12-14 | — | — | WO | disclosed |
| WO-2017003894-A1 | SUBSTITUTED TRIAZOLO BICYCLIC COMPOUNDS AS PDE2 INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2017-01-05 | — | — | WO | disclosed |
| US-20160137583-A1 | METHOD FOR PRODUCING ALPHA-HYDROXYCARBOXYLIC ACID ESTERS | EVONIK ROHM GMBH (DE) | 2016-05-19 | — | — | US | disclosed |
| EP-2970240-A1 | 3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES AS INHIBITORS OF MUTANT IDH | Novartis AG (CH) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014141104-A1 | 3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES AS INHIBITORS OF MUTANT IDH | NOVARTIS AG (CH) | 2014-09-18 | — | — | WO | disclosed |
| EP-1758883-B1 | Substituted 2-quinolyl-oxazoles useful as PDE4 inhibitors | SCHERING CORP (US) | 2011-11-02 | — | — | EP | disclosed |
| US-7745459-B2 | Quinolizinone compound and use thereof as HIV integrase inhibitor | JAPAN TOBACCO INC. (JP) | 2010-06-29 | — | — | US | disclosed |
| US-20060084665-A1 | Quinolizinone compound and use thereof as HIV integrase inhibitor | JAPAN TOBACCO INC. (JP) | 2006-04-20 | — | — | US | disclosed |