Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 11/20 | 0.59 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11498426 | 0.78 | NOTUM (0.53) | NOTUMPDK2TSHRLMNAKMT2A | |
| SCHEMBL6190865 | 0.77 | NOTUM (0.59) | NOTUMPDK2TSHRLMNAKMT2A | |
| SCHEMBL30413010 | 0.76 | NOTUM (0.58) | NOTUMPDK2TSHRLMNAKMT2A | |
| SCHEMBL9641641 | 0.76 | NOTUM (0.66) | NOTUMPDK2TSHRKMT2ANPC1 | |
| SCHEMBL2210038 | 0.76 | NOTUM (0.58) | NOTUMPDK2TSHRLMNAKMT2A | |
| SCHEMBL28299256 | 0.75 | NOTUM (0.53) | NOTUMTSHRLMNAKMT2ANPC1 | |
| Fenadiazole SCHEMBL555484 | 0.74 | NOTUM (0.61) | NOTUMPDK2TSHRLMNAKMT2A | |
| SCHEMBL7050954 | 0.74 | NOTUM (1.00) | NOTUMPDK2TSHRLMNAKMT2A | |
| SCHEMBL12479205 | 0.74 | NOTUM (0.61) | NOTUMPDK2TSHRLMNAKMT2A | |
| SCHEMBL4752346 | 0.74 | NOTUM (1.00) | NOTUMPDK2TSHRLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2200944-A1 | METHOD FOR REMOVING HYDRAZINE COMPOUNDS | E. I. du Pont de Nemours and Company (US) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009051958-A1 | METHOD FOR REMOVING HYDRAZINE COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-04-23 | — | — | WO | disclosed |