SCHEMBL28299256

SCHEMBL28299256

COc1ccccc1-c1ccccc1-c1nnco1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 6/20 0.53
ALDH1A1 P00352 4/20 0.51
HPGD P15428 1/20 0.51
MAPK1 P28482 1/20 0.51
KMT2A Q03164 3/20 0.51
L3MBTL1 Q9Y468 2/20 0.49
GAA P10253 1/20 0.49
TSHR P16473 2/20 0.49
LMNA P02545 1/20 0.49
MAPT P10636 1/20 0.49
NPC1 O15118 3/20 0.42
TP53 P04637 3/20 0.42
RAB9A P51151 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
KCNN4 O15554 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27493203 0.93 KMT2A (0.57) NOTUMALDH1A1HPGDMAPK1KMT2A
SCHEMBL13019358 0.75 KMT2A (0.54) NOTUMALDH1A1HPGDMAPK1KMT2A
SCHEMBL12125033 0.75 LMNA (0.62) NOTUMALDH1A1KMT2ATSHRLMNA
SCHEMBL13019948 0.75 NOTUM (0.56) NOTUMALDH1A1HPGDMAPK1KMT2A
SCHEMBL30599266 0.75 CA1 (0.67) ALDH1A1HPGDMAPK1KMT2AL3MBTL1
SCHEMBL11099503 0.75 CA1 (0.67) ALDH1A1HPGDMAPK1KMT2AL3MBTL1
SCHEMBL3643541 0.75 CA1 (0.67) ALDH1A1HPGDMAPK1KMT2AL3MBTL1
SCHEMBL3624979 0.75 NOTUM (0.59) NOTUMKMT2ATSHRLMNANPC1
SCHEMBL6190865 0.75 NOTUM (0.59) NOTUMALDH1A1HPGDKMT2AL3MBTL1
SCHEMBL2448308 0.74 NOTUM (0.60) NOTUMALDH1A1HPGDMAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104685416-B Photosensitive polymer combination, using its cured film preparation method, cured film, liquid crystal display device and organic EL display device 富士胶片株式会社 2019-05-14 CN disclosed