Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ANPEP | P15144 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13512332 | 0.88 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP1A2CYP2D6MAPTTSHR | |
| SCHEMBL16150930 | 0.86 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP1A2CYP2D6MAPTTSHR | |
| SCHEMBL16150929 | 0.86 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP1A2CYP2D6MAPTTSHR | |
| SCHEMBL3800686 | 0.83 | ANPEP (0.50) | SMN1; SMN2CYP1A2CYP2D6MAPTTSHR | |
| SCHEMBL3800689 | 0.83 | ANPEP (0.50) | SMN1; SMN2CYP1A2CYP2D6MAPTTSHR | |
| SCHEMBL7141122 | 0.79 | SMN1; SMN2 (0.58) | SMN1; SMN2CYP1A2CYP2D6MAPTTSHR | |
| SCHEMBL3799393 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2CYP1A2CYP2D6MAPTTSHR | |
| SCHEMBL3799389 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2CYP1A2CYP2D6MAPTTSHR | |
| SCHEMBL7361107 | 0.79 | SMN1; SMN2 (0.61) | SMN1; SMN2CYP1A2CYP2D6MAPTTSHR | |
| SCHEMBL2236636 | 0.79 | CHRM2 (0.60) | SMN1; SMN2TSHRANPEPNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262808-A2 | CHEMOKINE RECEPTOR MODULATORS | Altiris Therapeutics (US) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009121063-A2 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS (US) | 2009-10-01 | — | — | WO | disclosed |