Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3621526 | 0.85 | F2 (0.34) | NTRK1RETPDGFRBPDGFRAKDR | |
| SCHEMBL3627038 | 0.84 | F2 (0.33) | NTRK1RETPDGFRBPDGFRAKDR | |
| SCHEMBL3626388 | 0.80 | CA1 (0.34) | NTRK1RETPDGFRBPDGFRAKDR | |
| SCHEMBL3627781 | 0.80 | PDK1 (0.35) | NTRK1RETPDGFRBPDGFRAKDR | |
| SCHEMBL981028 | 0.79 | PDE3B (0.32) | — | |
| SCHEMBL3628329 | 0.79 | CA1 (0.32) | NTRK1RETPDGFRBPDGFRAKDR | |
| SCHEMBL978728 | 0.78 | EPHX2 (0.36) | TRPV1CA1CA2 | |
| SCHEMBL3629194 | 0.77 | CA1 (0.31) | CA1CA2F2F10PRSS1 | |
| SCHEMBL3625711 | 0.77 | GPBAR1 (0.32) | — | |
| SCHEMBL3627034 | 0.77 | PDK1 (0.34) | NTRK1RETPDGFRBPDGFRAKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2199287-A1 | SUBSTITUTED ISOXAZOLINE COMPOUND AND PEST CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2010-06-23 | — | — | EP | disclosed |