Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | PNP | P00491 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3625870 | 1.00 | POLA1 (0.63) | POLA1KDM4EPNPLMNATP53 | |
| SCHEMBL29559302 | 0.91 | POLA1 (0.66) | POLA1KDM4EPNPLMNATP53 | |
| SCHEMBL890293 | 0.91 | POLA1 (0.66) | POLA1KDM4EPNPLMNATP53 | |
| SCHEMBL16206605 | 0.89 | POLA1 (0.59) | POLA1KDM4EPNPLMNATP53 | |
| SCHEMBL3615728 | 0.89 | POLA1 (0.63) | POLA1KDM4EPNPLMNATP53 | |
| SCHEMBL3615734 | 0.89 | POLA1 (0.63) | POLA1KDM4EPNPLMNATP53 | |
| SCHEMBL20346237 | 0.88 | KDM4E (0.72) | POLA1KDM4EPNPLMNATP53 | |
| SCHEMBL264545 | 0.88 | KDM4E (0.72) | POLA1KDM4EPNPLMNATP53 | |
| SCHEMBL25507075 | 0.88 | KDM4E (0.72) | POLA1KDM4EPNPLMNATP53 | |
| SCHEMBL264546 | 0.88 | KDM4E (0.72) | POLA1KDM4EPNPLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851157-B1 | Oligonucleotide derivative, probe for detection of gene, and DNA chip | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2010-12-14 | — | — | US | disclosed |
| EP-1860115-A1 | OLIGONUCLEOTIDE DERIVATIVE, PROBE FOR DETECTION OF GENE, AND DNA CHIP | Tokyo Institute of Technology (JP) | 2007-11-28 | — | — | EP | disclosed |