Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.60 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.60 |
| ▸ | PNP | P00491 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29559302 | 1.00 | POLA1 (0.66) | POLA1KDM4ETAS1R3TAS1R1PNP | |
| SCHEMBL6327430 | 0.92 | POLA1 (0.64) | POLA1KDM4ETAS1R3TAS1R1PNP | |
| SCHEMBL3615728 | 0.92 | POLA1 (0.63) | POLA1KDM4ETAS1R3TAS1R1PNP | |
| SCHEMBL3615734 | 0.92 | POLA1 (0.63) | POLA1KDM4ETAS1R3TAS1R1PNP | |
| SCHEMBL3625876 | 0.91 | POLA1 (0.63) | POLA1KDM4ETAS1R3TAS1R1PNP | |
| SCHEMBL3625870 | 0.91 | POLA1 (0.63) | POLA1KDM4ETAS1R3TAS1R1PNP | |
| SCHEMBL25507075 | 0.91 | KDM4E (0.72) | POLA1KDM4ETAS1R3TAS1R1PNP | |
| SCHEMBL20346237 | 0.91 | KDM4E (0.72) | POLA1KDM4ETAS1R3TAS1R1PNP | |
| SCHEMBL264545 | 0.91 | KDM4E (0.72) | POLA1KDM4ETAS1R3TAS1R1PNP | |
| SCHEMBL12714741 | 0.91 | KDM4E (0.72) | POLA1KDM4ETAS1R3TAS1R1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110287427-A1 | 3'OH-UNBLOCKED, NUCLEOTIDES AND NUCLEOSIDES BASE MODIFIED WITH LABELS AND PHOTOCLEAVABLE, TERMINATING GROUPS AND METHODS FOR THEIR USE IN DNA SEQUENCING | LASERGEN, INC. (US) | 2011-11-24 | — | — | US | disclosed |
| US-7964352-B2 | 3′-OH unblocked nucleotides and nucleosides, base modified with labels and photocleavable, terminating groups and methods for their use in DNA sequencing | LASERGEN, INC. (US) | 2011-06-21 | — | — | US | disclosed |
| US-20090081686-A1 | PHOTOCLEAVABLE LABELED NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | AGILENT TECHNOLOGIES, INC. | 2009-03-26 | — | — | US | disclosed |