Trichloroacetic Acid

Trichloroacetic Acid

SCHEMBL3625877

ClCCl.O=C(O)C(Cl)(Cl)Cl

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.77
ALDH1A1 P00352 4/20 0.77
TP53 P04637 1/20 0.77
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trichloroacetic Acid SCHEMBL1331160 0.88
Trichloroacetic Acid SCHEMBL3220 0.88
Trichloroacetic Acid SCHEMBL38661501 0.88
Trichloroacetic Acid SCHEMBL10745837 0.88
Trichloroacetic Acid SCHEMBL1331955 0.88
Trichloroacetic Acid SCHEMBL10493657 0.88 TSHR (1.00) TSHRALDH1A1TP53CYP1A2CYP2D6
Trichloroacetic Acid SCHEMBL5311061 0.88 TSHR (1.00) TSHRALDH1A1TP53CYP1A2CYP2D6
Trichloroacetic Acid SCHEMBL10549726 0.86 TSHR (0.67) TSHRALDH1A1TP53CYP1A2
Trichloroacetic Acid SCHEMBL10358466 0.86 TSHR (0.67) TSHRALDH1A1TP53CYP1A2CYP2D6
Trichloroacetic Acid SCHEMBL11393443 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114686481-B Interference RNA for inhibiting CFD expression and preparation method and application thereof 北京键凯科技股份有限公司 2023-08-15 CN claimed
CN-106008136-A Preparation method of 6,6,12,12-tetramethyl-6,12-dihydroindeno[1,2-b] fluorene 李金铃 2016-10-12 CN claimed
CN-104628805-B A kind of preparation method of amphipathic fat nucleic acid 中国石油大学(华东) 2016-06-08 CN claimed
CN-119462801-A Photosensitive amphiphilic compound containing coumarin unit, and preparation method and application thereof 中国石油大学(华东) 2025-02-18 CN disclosed
WO-2024140596-A1 SIRNA MOLECULE FOR REGULATING ACTIVITY OF XDH GENE 大睿生物医药科技(上海)有限公司 2024-07-04 WO disclosed
CN-113929724-B Nucleoside compound, pharmaceutical composition and application thereof 周雨恬 2024-05-31 CN disclosed
US-20240166674-A1 PHOSPHORAMIDITE ACTIVATOR FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2024-05-23 US disclosed
US-20240166689-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-05-23 US disclosed
WO-2024093907-A1 LIGAND FOR DELIVERING SIRNA TO EYE AND CENTRAL NERVOUS SYSTEM 大睿生物医药科技(上海)有限公司 2024-05-10 WO disclosed
WO-2024093947-A1 PRODRUG FOR DELIVERING SIRNA INTO CELL 大睿生物医药科技(上海)有限公司 2024-05-10 WO disclosed
CN-116917477-B Targeting ligands containing N-acetylgalactosamine 大睿生物医药科技(上海)有限公司 2024-04-09 CN disclosed
EP-0685457-A1 GLYCEROL DERIVATIVE, DEVICE AND PHARMACEUTICAL COMPOSITION NIPPON SHINYAKU COMPANY, LIMITED (JP) 1995-12-06 EP disclosed
EP-0685234-A1 DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER NIPPON SHINYAKU COMPANY, LIMITED (JP) 1995-12-06 EP disclosed
US-5427929-A Enzyme pretreatment AMGEN INC. (US) 1995-06-27 US disclosed
EP-0321548-A4 NOVEL AMPHIPHILIC NUCLEIC ACID CONJUGATES 1991-01-30 EP disclosed
US-4904582-A Novel amphiphilic nucleic acid conjugates SYNTHETIC GENETICS (US) 1990-02-27 US disclosed
WO-1989005853-A1 NUCLEIC ACID CHELATE CONJUGATE AS THERAPEUTIC AND DIAGNOSTIC AGENTS SYNTHETIC GENETICS (US) 1989-06-29 WO disclosed
EP-0321548-A1 NOVEL AMPHIPHILIC NUCLEIC ACID CONJUGATES SYNTHETIC GENETICS (US) 1989-06-28 EP disclosed
WO-1988009810-A1 NOVEL AMPHIPHILIC NUCLEIC ACID CONJUGATES SYNTHETIC GENETICS (US) 1988-12-15 WO disclosed
US-4701304-A Apparatus for automated synthesis of peptides APPLIED PROTEIN TECHNOLOGIES, INC. (US) 1987-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240166674-A1 PHOSPHORAMIDITE ACTIVATOR ITPA, INPP5D, INPP5B TSHR 1564/4885ALDH1A1 3801/4885TP53 2360/4885
US-20240166689-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD VIP, NGLY1, GLP1R TSHR 1056/4885ALDH1A1 4857/4885TP53 2654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.