Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3628900 | 1.00 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL3629343 | 1.00 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL3627227 | 0.91 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL3628438 | 0.91 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL3627956 | 0.91 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL3210316 | 0.90 | HSD11B1 (0.81) | HSD11B1 | |
| Hsd-016 SCHEMBL3219515 | 0.88 | HSD11B1 (1.00) | HSD11B1 | |
| Hsd-016 SCHEMBL29358944 | 0.88 | HSD11B1 (1.00) | HSD11B1 | |
| Hsd-016 SCHEMBL3213640 | 0.88 | HSD11B1 (1.00) | HSD11B1 | |
| Hsd-016 SCHEMBL3212579 | 0.88 | HSD11B1 (1.00) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010141550-A2 | 11-BETA HSD1 INHIBITORS | WYETH LLC (US) | 2010-12-09 | — | — | WO | claimed |
| WO-2010141550-A2 | 11-BETA HSD1 INHIBITORS | WYETH LLC (US) | 2010-12-09 | — | — | WO | disclosed |