Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.80 |
| ▸ | IGLV6-57 | P01721 | 6/20 | 0.80 |
| ▸ | HPGD | P15428 | 4/20 | 0.80 |
| ▸ | GLA | P06280 | 4/20 | 0.80 |
| ▸ | ATM | Q13315 | 4/20 | 0.80 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.80 |
| ▸ | CASP1 | P29466 | 3/20 | 0.80 |
| ▸ | CASP7 | P55210 | 3/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.80 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.80 |
| ▸ | AR | P10275 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144250 | 0.94 | AR (0.75) | ALDH1A1IGLV6-57HPGDGLAATM | |
| SCHEMBL29551746 | 0.94 | AR (0.75) | ALDH1A1IGLV6-57HPGDGLAATM | |
| SCHEMBL29362472 | 0.89 | ALDH1A1 (1.00) | ALDH1A1IGLV6-57HPGDGLAATM | |
| SCHEMBL67108 | 0.89 | ALDH1A1 (1.00) | ALDH1A1IGLV6-57HPGDGLAATM | |
| SCHEMBL384286 | 0.89 | ALDH1A1 (1.00) | ALDH1A1IGLV6-57HPGDGLAATM | |
| SCHEMBL5918266 | 0.84 | AR (0.61) | ALDH1A1IGLV6-57HPGDGLAATM | |
| SCHEMBL1771392 | 0.83 | AR (0.59) | ALDH1A1IGLV6-57HPGDGLAATM | |
| Sulfuric Acid SCHEMBL25246703 | 0.82 | ALDH1A1 (0.84) | ALDH1A1IGLV6-57HPGDGLAATM | |
| Sulfuric Acid SCHEMBL31121932 | 0.82 | ALDH1A1 (0.84) | ALDH1A1IGLV6-57HPGDGLAATM | |
| SCHEMBL6743615 | 0.82 | ALDH1A1 (0.63) | ALDH1A1IGLV6-57HPGDGLAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188634-A1 | FLUORESCENCE RESONANCE ENERGY TRANSFER DETECTION WITH NANOPARTICLES | Carestream Health, Inc. (US) | 2010-05-26 | — | — | EP | disclosed |
| WO-2010016858-A2 | MOLECULAR IMAGING PROBES | CARESTREAM HEALTH, INC. (US) | 2010-02-11 | — | — | WO | disclosed |
| WO-2009032236-A1 | FLUORESCENCE RESONANCE ENERGY TRANSFER DETECTION WITH NANOPARTICLES | CARESTREAM HEALTH, INC. (US) | 2009-03-12 | — | — | WO | disclosed |