SCHEMBL3626463

SCHEMBL3626463

O=C1c2cc(Cl)c(Cl)cc2C(=O)N1c1ccc(C(Br)(c2ccc(N3C(=O)c4cc(Cl)c(Cl)cc4C3=O)cc2)c2ccc(N3C(=O)c4cc(Cl)c(Cl)cc4C3=O)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 7/20 0.58
CA12 O43570 4/20 0.58
CA1 P00915 4/20 0.58
CA2 P00918 3/20 0.57
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
ESR1 P03372 2/20 0.44
ESR2 Q92731 2/20 0.44
RAD51 Q06609 1/20 0.42
NPC1 O15118 1/20 0.40
ALDH1A1 P00352 1/20 0.40
TSHR P16473 1/20 0.40
CASP1 P29466 1/20 0.40
RAB9A P51151 1/20 0.40
CASP7 P55210 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2357830 0.84 CA9 (0.61) CA9CA12CA1CA2MEN1
SCHEMBL3694840 0.83 CA9 (0.55) CA9CA12CA1CA2MEN1
SCHEMBL5647824 0.78 ESR1 (0.70) CA9CA12CA1CA2MEN1
SCHEMBL5198978 0.78 ALDH1A1 (0.64) CA9CA12CA1CA2MEN1
SCHEMBL27475071 0.78 CA9 (0.62) CA9CA12CA1CA2MEN1
SCHEMBL28302934 0.77 CA9 (0.57) CA9CA12CA1CA2MEN1
SCHEMBL29710383 0.77 CA9 (0.66) CA9CA12CA1CA2MEN1
SCHEMBL9633890 0.77 CA9 (0.66) CA9CA12CA1CA2MEN1
SCHEMBL374398 0.76 CA9 (0.60) CA9CA12CA1CA2MEN1
SCHEMBL522210 0.76 CA9 (0.75) CA9CA12CA1CA2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10144849-B2 Polishing composition and polishing method using the same FUJIMI INCORPORATED (JP) 2018-12-04 US disclosed
US-20100301014-A1 Polishing Composition and Polishing Method Using the Same FUJIMI INCORPORATED (JP) 2010-12-02 US disclosed
EP-2237311-A1 POLISHING COMPOSITION AND POLISHING METHOD USING THE SAME FUJIMI INCORPORATED (JP) 2010-10-06 EP disclosed