Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | GAA | P10253 | 6/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2772880 | 0.77 | MEN1 (0.48) | MEN1KMT2ATDP1ALDH1A1GAA | |
| SCHEMBL294734 | 0.71 | MEN1 (0.50) | MEN1KMT2ATDP1ALDH1A1HTT | |
| SCHEMBL293567 | 0.71 | KMT2A (0.45) | MEN1KMT2ATDP1ALDH1A1HTT | |
| SCHEMBL295358 | 0.70 | MEN1 (0.46) | MEN1KMT2ATDP1ALDH1A1HTT | |
| SCHEMBL294156 | 0.69 | KMT2A (0.49) | MEN1KMT2ATDP1ALDH1A1HTT | |
| SCHEMBL295244 | 0.69 | KMT2A (0.47) | MEN1KMT2ATDP1ALDH1A1HTT | |
| SCHEMBL2776092 | 0.68 | POLB (0.49) | MEN1KMT2ATDP1ALDH1A1GAA | |
| SCHEMBL2772039 | 0.68 | MEN1 (0.46) | MEN1KMT2ATDP1ALDH1A1GAA | |
| SCHEMBL2776020 | 0.66 | KDM4E (0.46) | MEN1KMT2ATDP1ALDH1A1GAA | |
| SCHEMBL295977 | 0.65 | ALDH1A1 (0.45) | MEN1KMT2ATDP1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240474-B1 | CYCLIC PYRIDYL-N-(1,3,4)-THIADIAZOL-2-YL-BENZENE SULFONAMIDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2012-03-14 | — | — | EP | disclosed |