Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | FDPS | P14324 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH4 | P08319 | 1/20 | 0.31 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7075113 | 0.81 | LMNA (0.35) | SPHK1LMNADNM1TSHRTHRB | |
| SCHEMBL29205016 | 0.79 | LMNA (0.41) | SPHK1LMNADNM1TSHRTHRB | |
| SCHEMBL1261947 | 0.79 | LMNA (0.41) | SPHK1LMNADNM1TSHRTHRB | |
| SCHEMBL10436559 | 0.79 | LMNA (0.41) | SPHK1LMNADNM1TSHRTHRB | |
| SCHEMBL11357516 | 0.79 | LMNA (0.41) | SPHK1LMNADNM1TSHRTHRB | |
| SCHEMBL5574289 | 0.79 | LMNA (0.41) | SPHK1LMNADNM1TSHRTHRB | |
| SCHEMBL11827545 | 0.79 | LMNA (0.41) | SPHK1LMNADNM1TSHRTHRB | |
| SCHEMBL3740402 | 0.79 | LMNA (0.41) | SPHK1LMNADNM1TSHRTHRB | |
| SCHEMBL28612612 | 0.79 | LMNA (0.41) | SPHK1LMNADNM1TSHRTHRB | |
| SCHEMBL11182983 | 0.79 | LMNA (0.41) | SPHK1LMNADNM1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2147298-A1 | DETECTION OF CANCER MARKERS | Polytechnic University (US) | 2010-01-27 | — | — | EP | disclosed |
| US-20090318788-A1 | DETECTION OF CANCER MARKERS | POLYTECHNIC UNIVERSITY | 2009-12-24 | — | — | US | disclosed |
| WO-2008134511-A1 | DETECTION OF CANCER MARKERS | POLYTECHNIC UNIVERSITY (US) | 2008-11-06 | — | — | WO | disclosed |