⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530035 | 0.88 | TRIM24 (0.35) | — | |
| SCHEMBL560000 | 0.88 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL11474386 | 0.75 | — | — | |
| SCHEMBL3696538 | 0.71 | CES1 (0.52) | — | |
| SCHEMBL1486117 | 0.69 | MAOA (0.41) | — | |
| SCHEMBL3627989 | 0.67 | — | — | |
| SCHEMBL9654236 | 0.64 | — | — | |
| SCHEMBL11250410 | 0.61 | — | — | |
| SCHEMBL4282290 | 0.59 | TRIM24 (0.36) | — | |
| SCHEMBL9134442 | 0.57 | TRIM24 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178201-A | N, N' -diaryl propane diamide compound, preparation method and application | 广州大学 | 2023-05-30 | — | — | CN | claimed |
| CN-116178201-A | N, N' -diaryl propane diamide compound, preparation method and application | 广州大学 | 2023-05-30 | — | — | CN | disclosed |
| US-7674793-B2 | Tricyclic dihydropyrazines as potassium channel openers | JANSSEN PHARMACEUTICA NV (BE) | 2010-03-09 | — | — | US | disclosed |
| US-7674793-B2 | Tricyclic dihydropyrazines as potassium channel openers | JANSSEN PHARMACEUTICA NV (BE) | 2010-03-09 | — | — | US | disclosed |
| EP-1994012-B1 | NOVEL TRICYCLIC DIHYDROPYRAZINES AS POTASSIUM CHANNEL OPENERS | JANSSEN PHARMACEUTICA NV (BE) | 2009-12-09 | — | — | EP | disclosed |
| EP-1994012-A1 | NOVEL TRICYCLIC DIHYDROPYRAZINES AS POTASSIUM CHANNEL OPENERS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007095424-A1 | NOVEL TRICYCLIC DIHYDROPYRAZINES AS POTASSIUM CHANNEL OPENERS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-08-23 | — | — | WO | disclosed |
| US-20070191382-A1 | NOVEL TRICYCLIC DIHYDROPYRAZINES AS POTASSIUM CHANNEL OPENERS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-08-16 | — | — | US | disclosed |
| US-20070191382-A1 | NOVEL TRICYCLIC DIHYDROPYRAZINES AS POTASSIUM CHANNEL OPENERS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-08-16 | — | — | US | disclosed |
| US-7022452-B2 | Contrast enhanced photolithography | AGILENT TECHNOLOGIES, INC. (US) | 2006-04-04 | — | — | US | disclosed |
| US-20040043328-A1 | Contrast enhanced photolithography | AGILENT TECHNOLOGIES, INC. | 2004-03-04 | — | — | US | disclosed |
| US-5326826-A | Binder | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-07-05 | — | — | US | disclosed |
| US-5302488-A | Radiation-sensitive polymers containing naphthoquinone-2-diazide-4-sulfonyl groups and their use in a positive working recording material | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-12 | — | — | US | disclosed |
| EP-0371240-B1 | USE OF N-PHENYL-SUBSTITUTED OXAZINDIONES AS HERBICIDES AND N-PHENYL-SUBSTITUTED OXAZINDIONES AND SOME PROCESSES FOR THEIR PRODUCTION | BAYER AG (DE) | 1993-06-16 | — | — | EP | disclosed |
| EP-0529402-A1 | N-(3-alkylthio-phenyl)-oxazindiones as herbicides | BAYER AG (DE) | 1993-03-03 | — | — | EP | disclosed |
| US-5164498-A | Herbicidal N-phenyl-substituted oxazinediones | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-17 | — | — | US | disclosed |
| US-5061310-A | HERBICIDAL N-PHENYL-SUBSTITUTED OXAZINEDIONES AND OXAZINONETHIONES | BAYER AKTIENGESELLSCHAFT (DE) | 1991-10-29 | — | — | US | disclosed |
| EP-0442755-A2 | Alternating copolymer of styrene and 2-diazo-4-cyclopentene-1,3-dione | Wu, Chengjiu (US) | 1991-08-21 | — | — | EP | disclosed |
| EP-0371240-A1 | Use of N-phenyl-substituted oxazindiones as herbicides and N-phenyl-substituted oxazindiones and some processes for their production | BAYER AG (DE) | 1990-06-06 | — | — | EP | disclosed |