⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29029022 | 0.88 | PARP1 (0.40) | — | |
| SCHEMBL28490250 | 0.83 | PARP1 (0.37) | — | |
| SCHEMBL7970843 | 0.73 | PARP1 (0.59) | — | |
| SCHEMBL1724206 | 0.70 | — | — | |
| SCHEMBL17993348 | 0.70 | — | — | |
| SCHEMBL22214107 | 0.70 | — | — | |
| SCHEMBL15741258 | 0.70 | — | — | |
| SCHEMBL3651169 | 0.70 | — | — | |
| SCHEMBL6837616 | 0.69 | PARP1 (0.54) | — | |
| SCHEMBL6645139 | 0.69 | GDA (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204413-B1 | DIHYDROQUINAZOLIN-2-ONE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS USEFUL IN THE TREATMENT OF HIV | MERCK SHARP & DOHME LLC (US) | 2024-09-25 | — | — | EP | claimed |
| US-11648250-B2 | Tetrahydroquinazoline derivatives as selective cytotoxic agents | MERCK SHARP & DOHME LLC (US) | 2023-05-16 | — | — | US | claimed |
| EP-0399856-B1 | Pteridin-4 (3H)-ones, processes for their preparation and medicaments containing them | LIPHA (FR) | 1995-08-09 | — | — | EP | claimed |
| EP-0399856-A1 | Pteridin-4 (3H)-ones, processes for their preparation and medicaments containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1990-11-28 | — | — | EP | claimed |
| EP-4665868-A2 | METHODS FOR MULTIPLEXED IMAGING AND DETECTION OF TARGETS | President and Fellows of Harvard College (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2025217257-A1 | ENGINEERED CIRCULARIZED PEGRNAS AND USES THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2025-10-16 | — | — | WO | disclosed |
| WO-2025021829-A1 | MULTIVALENT CARGO-CARRYING COMPLEXES AND USES THEREOF | ASTRAZENECA AB (SE) | 2025-01-30 | — | — | WO | disclosed |
| WO-2025021831-A1 | MULTIVALENT CARGO-CARRYING COMPLEXES AND USES THEREOF | ASTRAZENECA AB (SE) | 2025-01-30 | — | — | WO | disclosed |
| WO-2025021833-A1 | MULTIVALENT CARGO-CARRYING COMPLEXES AND USES THEREOF | ASTRAZENECA AB (SE) | 2025-01-30 | — | — | WO | disclosed |
| EP-4490316-A1 | MULTIPLEX FLUORESCENT CELLULAR AND TISSUE IMAGING WITH DNA ENCODED THERMAL CHANNELS AND USES THEREOF | President And Fellows Of Harvard College (US) | 2025-01-15 | — | — | EP | disclosed |
| WO-2025006923-A2 | SINGLE-STRANDED NUCLEIC ACID ANALOGS FOR USE AS MUTATION RESISTANT ANTIBACTERIAL TREATMENT | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2025-01-02 | — | — | WO | disclosed |
| EP-4419536-A1 | OLIGONUCLEOTIDES WITH 2'-DEOXY-2'-F-2'-C-METHYL NUCLEOTIDES | Alnylam Pharmaceuticals, Inc. (US) | 2024-08-28 | — | — | EP | disclosed |
| US-20020016309-A1 | Imidazopyridine and imidazopyrimidine antiviral agents | BRISTOL-MEYERS SQUIBB COMPANY | 2002-02-07 | — | — | US | disclosed |
| WO-2001095910-A1 | IMIDAZOPYRIDINE AND IMIDAZOPYRIMIDINE ANTIVIRAL AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |
| EP-1098644-A1 | SUBSTITUTED BENZIMIDAZOLE ANTIVIRAL AGENTS | Bristol-Myers Squibb Company (US) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000004900-A1 | SUBSTITUTED BENZIMIDAZOLE ANTIVIRAL AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-02-03 | — | — | WO | disclosed |
| EP-0399856-B1 | Pteridin-4 (3H)-ones, processes for their preparation and medicaments containing them | LIPHA (FR) | 1995-08-09 | — | — | EP | disclosed |
| US-5270465-A | 4(3H)-pteridinone compounds | LIPHA, LYONNAISE INDUSTRILLE PHARMACEUTIQUE (FR) | 1993-12-14 | — | — | US | disclosed |
| US-5167949-A | Antiallergic | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1992-12-01 | — | — | US | disclosed |
| EP-0399856-A1 | Pteridin-4 (3H)-ones, processes for their preparation and medicaments containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1990-11-28 | — | — | EP | disclosed |