Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.44 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.42 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MLNR | O43193 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1476522 | 1.00 | TSHR (0.67) | TSHRHTTDNM1THRBACHE | |
| Hydrochloric Acid SCHEMBL1547473 | 1.00 | TSHR (0.67) | TSHRHTTDNM1THRBACHE | |
| Hydrochloric Acid SCHEMBL5381892 | 1.00 | TSHR (0.67) | TSHRHTTDNM1THRBACHE | |
| SCHEMBL4931019 | 1.00 | TSHR (0.67) | TSHRHTTDNM1THRBACHE | |
| SCHEMBL1476825 | 1.00 | TSHR (0.67) | TSHRHTTDNM1THRBACHE | |
| Hydrochloric Acid SCHEMBL8192652 | 1.00 | TSHR (0.67) | TSHRHTTDNM1THRBACHE | |
| SCHEMBL1491883 | 1.00 | TSHR (0.67) | TSHRHTTDNM1THRBACHE | |
| SCHEMBL11961430 | 1.00 | TSHR (0.67) | TSHRHTTDNM1THRBACHE | |
| SCHEMBL3694453 | 1.00 | TSHR (0.67) | TSHRHTTDNM1THRBACHE | |
| Hydrochloric Acid SCHEMBL28573008 | 1.00 | TSHR (0.67) | TSHRHTTDNM1THRBACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109796616-B | Bionic polymer, method for manufacturing durable double-bionic polymer coating and application | 西北大学 | 2020-04-10 | — | — | CN | claimed |
| US-20230210728-A1 | ENERGY RAY-CURABLE COATING MATERIAL FOR THREE-DIMENSIONAL SHAPED ARTICLES, ENERGY RAY-CURABLE MATERIAL KIT FOR THREE-DIMENSIONAL SHAPING INCLUDING SAME, THREE-DIMENSIONAL SHAPED ARTICLE USING SAME, AND METHOD OF PRODUCTION THEREOF | KURARAY NORITAKE DENTAL INC. (JP) | 2023-07-06 | — | — | US | disclosed |
| WO-2021132699-A1 | ENERGY RAY-CURABLE COATING MATERIAL FOR THREE-DIMENSIONAL MOLDING, ENERGY RAY-CURABLE MATERIAL KIT FOR THREE-DIMENSIONAL MOLDING CONTAINING SAID SAME, THREE-DIMENSIONAL MOLDED PRODUCT OBTAINED USING SAME, AND METHOD FOR PRODUCING SAME | クラレノリタケデンタル株式会社 | 2021-07-01 | — | — | WO | disclosed |
| CN-109796616-B | Bionic polymer, method for manufacturing durable double-bionic polymer coating and application | 西北大学 | 2020-04-10 | — | — | CN | disclosed |
| EP-1787623-B1 | Dental polymerizable composition | KURARAY NORITAKE DENTAL INC (JP) | 2014-03-26 | — | — | EP | disclosed |
| US-7683103-B2 | Dental polymerizable composition | KURARAY MEDICAL INC. (JP) | 2010-03-23 | — | — | US | disclosed |
| WO-2008074702-A1 | METHOD FOR CROSS-COUPLING USING METAL NANOPARTICLES AS THE CATALYST | BASF SE (DE) | 2008-06-26 | — | — | WO | disclosed |
| US-20080039592-A1 | Dental Polymerizable Composition | KURARAY MEDICAL INC. (JP) | 2008-02-14 | — | — | US | disclosed |
| EP-1787623-A1 | DENTAL POLYMERIZABLE COMPOSITION | Kuraray Medical Inc. (JP) | 2007-05-23 | — | — | EP | disclosed |
| EP-0878198-B1 | TABLETS CONTAINING AN ANION EXCHANGE RESIN | HISAMITSU PHARMACEUTICAL CO (JP) | 2002-02-06 | — | — | EP | disclosed |
| US-6022533-A | TABLET OBTAINED BY ADMIXING SILICON DIOXIDE, CRYSTALLINE CELLULOSE, A CARRIER AND NONCROSSLINKED ANION EXCHANGE RESIN SUCH AS POLY(ACRYLOYLOXYETHYL-N,N-DIMETHYL-N-BENZYLAMMONIUM CHLORIDE) WITHOUT WATER; USE AS CHOLESTEROL DEPRESSANT | HISAMITSU PHARMACEUTICAL CO. INC. (JP) | 2000-02-08 | — | — | US | disclosed |
| EP-0878198-A1 | TABLETS CONTAINING ANION EXCHANGE RESIN | HISAMITSU PHARMACEUTICAL CO. INC. (JP) | 1998-11-18 | — | — | EP | disclosed |
| EP-0076131-B1 | HUMIDITY SENSOR AND METHOD FOR PREPARING A HUMIDITY SENSOR | Hitachi, Ltd. (JP) | 1986-04-09 | — | — | EP | disclosed |
| US-4473813-A | CROSSLINKED SILICONE RESIN | HITACHI, LTD. (JP) | 1984-09-25 | — | — | US | disclosed |
| EP-0076131-A1 | Humidity sensor and method for preparing a humidity sensor | Hitachi, Ltd. (JP) | 1983-04-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210728-A1 | ENERGY RAY-CURABLE COATING MATERIAL FOR THREE-DIMENSIONAL SHAPED ARTICLES, ENERGY RAY-CURABLE MATERIAL KIT FOR THREE-DIMENSIONAL SHAPING INCLUDING SAME, THREE-DIMENSIONAL SHAPED ARTICLE USING SAME, AND METHOD OF PRODUCTION THEREOF | KIT, SETD7, SETDB1 | ACHE 1678/4885CHRM2 2997/4885CHRM1 2445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.